Postdoctoral Scientist

San Antonio, Texas
April 30 2018
Position Type
Full Time
Organization Type
Job Type

Saving Lives With the Power of Scientific Discovery. We make today’s discoveries possible of becoming tomorrow’s cures.

Texas Biomedical Research Institute is one of the world's leading independent biomedical research institutions dedicated to advancing global human health through innovative biomedical research.  Texas Biomedical Research Institute aims to unravel the mysteries of chronic and infectious diseases through innovative thinking, creative problem solving and cutting edge technologies.  Since its founding in 1941 by Thomas B. Slick Jr., the Texas Biomedical Research Institute has gained worldwide recognition in scientific and academic communities for the quality of its basic research.

Our scientists work each and every day to improve human health by being a world leader in lifestyle and infectious disease research. Each year, our scientists are engaged in more than 200 research projects and publish well over 100 articles in the international scientific literature.

Located on a 200-acre campus on the northwest side of San Antonio, Texas, Texas Biomed partners with hundreds of researchers and institutions around the world, targeting advances in the fight against cardiovascular disease, diabetes, obesity, cancer, psychiatric disorders, problems of pregnancy, AIDS, hepatitis, malaria, parasitic infections and a host of other infectious diseases.  Its staff of more than 300 employees includes a multidisciplinary team of approximately 84 doctoral-level scientists who lead more than 200 major research projects.

Job Summary


We are looking for a talented, highly motivated postdoctoral researcher to join the laboratory of Dr. Melanie Carless to study the genetic and epigenetic contributions to complex diseases and establish related translational models. Our laboratory focuses on complex diseases, such as cardiometabolic and psychiatric diseases, which are associated with high mortality and morbidity rates. The primary project will incorporate next-generation sequencing, stem cell culture, and epigenetic editing technologies to investigate the role of DNA methylation in obesity and related phenotypes. Additional ongoing projects in the laboratory incorporate similar technologies to better understand the role of microRNAs in neuropsychiatric disorders and to establish potential mechanisms of treatment using human and non-human primate animal models.  The successful applicant will join a dynamic research program aimed at defining causal epigenetic signatures of chronic complex diseases and developing therapies aimed at combatting these. The applicant will report to Dr. Melanie Carless, and will be expected to conduct laboratory-based research as well as prepare and publish scientific manuscripts. They will be trained in experimental techniques and scientific communication, and mentorship will be provided for career advancement.

Requirements for this position are: PhD in genetics, biomedicine, molecular biology, neuroscience, or related discipline. Substantial experience with cell culture techniques. Good oral and written communication skills.  Preferred: Experience in stem cell reprogramming, maintenance and/or differentiation. Experience with gene-editing tools, molecular biology, fluorescence imaging and analysis, nucleic acid and protein extraction, next-generation sequencing, bioinformatics, and/or animal models is desirable but not mandatory.

This is a full-time salaried (exempt) position. Texas Biomed is committed to a drug-free workplace.  Pre-employment drug screen is required.

Interested applicants can apply online at Application packets are accepted electronically or in hard copy.  A completed application packet is a requirement for all positions.  Incomplete applications will not be accepted. Equal Employment Opportunity/M/F/Disability/Protected Veteran Status

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