Postdoctoral positions at New York University to study ion channels in immunity
Postdoctoral positions are available in the Feske lab at New York University School of Medicine (NYUSoM) to study the role of ion channels in immune responses to infection, self (autoimmunity) and/or tumors.
The Feske has long-standing expertise in investigating calcium signaling pathways in cells of the immune system. We study the molecular regulation of calcium release-activated channels (CRAC) formed by ORAI and STIM proteins and investigate their role in the physiology of immune cells. We use mice with targeted deletion of CRAC channels and human patients with mutations in CRAC channel genes to investigate how calcium signals control immune responses to infection and tumors, and in autoimmunity and inflammation. Our research is published in leading journals including Nature, New England Journal of Medicine, Immunity, Nature Immunology, Nature Communications, J Exp Med, J Clin Invest and PNAS. For more information, please visit: http://labs.pathology.med.nyu.edu/feske-lab/.
Besides CRAC channels, other ion channels are expressed in T cells and other immune cells that control their function. The Feske lab is systematically investigating which ion channels regulate adaptive and innate immune responses to pathogens, tumors, and self. For these projects, we are seeking highly motivated and creative postdoctoral scientists to elucidate the molecular mechanisms of ion channel function in immune cell and their role in immune responses in vitro and in vivo using animal models of immunity.
Candidates should have a recent MD, PhD or MD/PhD degree and a strong background in immunology, specifically the use of animal models or signal transduction. Candidates with experience in ion channel function in immune cells or related cell types are especially encouraged to apply. A background in molecular and cell biology is desired. Please send a cover letter explaining relevant work experience and interests, a CV, and the contact information of three references to Dr. Feske at firstname.lastname@example.org.