Scientist, Immunology/Neuroimmunology

South San Francisco, California
April 10 2018
Position Type
Full Time
Organization Type

At Alector, our mission is to harness the power of the immune system to cure neurodegeneration and cancer. Our team integrates knowledge in human genetics, bioinformatics, immunology, neurobiology, protein biochemistry and engineering, drug development, and business to help us discover and develop novel therapeutics.

We are supported by leading investors - including Orbimed, Polaris, Google Ventures, Topspin, The Dementia Discovery Fund and we count some of the most innovative pharma companies such as AbbVie, Merck, and Amgen as our strategic backers and partners.

Would you like to take part in creating new therapies that really make a difference in patients' lives? Do you desire both autonomy and collaboration in tackling scientific challenges that interest you? Would you like to be part of a talented team where everyone has a voice?

Use your scientific skills to help us achieve our mission of saving lives by curing neurodegenerative diseases.

As a Scientist for the Immuno-Neurology team, you’ll work closely with other scientists in preclinical research and development, leading a target discovery project from the ground up. You will support other ongoing programs and your work will be central to Alector’s strategic goals. As an early hire, you’ll be influential in championing and developing Alector’s culture.

During the first year, your goals will include:

  • Independently leading a high-priority target discovery project from-end-to-end, from high-level design and planning to running experiments, assessing results and identifying the critical path forward to a fast go/no-go decision within a year of project start
  • Being a partner to both academic collaborators and contract research organizations to ensure successful joint efforts
  • Collaborating within and across teams, including mentoring others on your areas of expertise so that they can learn from your skills and experience
  • Analyzing current scientific literature to help identify new targets or new strategies for existing targets


  • PhD with at least 3 years of postdoctoral or equivalent industry experience
  • Expertise in isolation and characterization of primary immune cells (myeloid cells) of rodent and/or human origin
  • Extensive experience with basic tissue culture and development of functional in vitro assays
  • Up-to-date knowledge of the field of innate immunity and signaling pathways
  • Authoritative knowledge in the design, validation and execution of in vitro and ex vivo flow cytometry-based phenotypic and functional characterization of immune cell populations
  • Excellent written and oral communication skills
  • Proficiency in both immunology and neurology (preferred)

Alector is a phenomenal place to learn and experiment. If you excel in a dynamic environment where everyone is committed to finding a cure, where you’ll drive growth, this is the role for you. There is no limit to how far you can go with us.

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