Postdoc positions in CRISPR cancer applications at the Hart Lab at MD Anderson Cancer Center

MD Anderson Cancer Center
Houston, Texas
At or above NIH postdoc scale
April 10 2018
Position Type
Full Time
Organization Type
Job Type

Postdoctoral positions in CRISPR applications to cancer systems biology are available immediately in the Department of Bioinformatics and Computational Biology (DBCB) at The University of Texas MD Anderson Cancer Center in Houston, TX. CRISPR has revolutionized the molecular biology of cancer by rendering the human genome tractable, and the Hart Lab is pushing the state of the art in the design, assay, and integrated analysis of CRISPR screens for cancer targeting and functional genomics. We are studying how gene essentiality varies by tissue type and genetic context, how genetic mutations modulate drug efficacy, and how tumor cells adapt to survive the severe selection pressure imposed by chemotherapy. We and our collaborators touch every aspect of human functional genomics, from discovery and validation of new gene function in cell lines to predicting and targeting tumor vulnerabilities in clinical trials.

We are seeking self-motivated candidates from varied backgrounds who are looking to take the next step in their careers at a world-class research institution. The University of Texas MD Anderson Cancer Center is ranked No. 1 in cancer care in the United States by U.S. News and World Report, and also No. 1 in the number of awarded grants from the National Cancer Institute. It offers excellent cancer research training programs and the unmatched scientific environment of the Texas Medical Center, the world’s largest medical center that contains over 50 biomedical institutions for patient care, basic and translational research, including MD Anderson Cancer Center, Baylor College of Medicine, and Rice University.

We are looking for candidates with a background or strong interest in high-throughput biology in model organisms and/or cell lines, and ideally experience with packaging and handling lentivirus. If you have a systems biology mindset and a drive to make your mark in one of the most exciting frontiers in biomedical research today, send us your CV! Candidates having or looking to learn the computational skills to analyze their own data are particularly welcome.

Interested candidates are encouraged to send a CV, a statement of research interests, and contact information for three references to Traver Hart by email at, with the subject line “Hart Lab Postdoc Application”.

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