Bioinformatics Research Scientist – Developmental Neurobiology

Employer
St. Jude Children's Research Hospital
Location
Memphis, Tennessee
Salary
DOE
Posted
April 05 2018
Organization Type
Non-Profit

The World’s Brightest Minds Always Innovate

At St. Jude Children’s Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That’s why we provide world-class facilities. State-of-the-art technologies. Extraordinary support. And a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve. Quite simply, at St. Jude, we encourage you to dream big, and we give you everything you need to be the force behind our cures.

Bioinformatics Research Scientist – Developmental Neurobiology

Memphis, TN

Overview

St. Jude Children’s Research Hospital’s Department of Developmental Neurobiology is looking for a highly motivated bioinformatics research scientist as the key analyst for the epigenomics and single cell sequencing projects of the Department of Developmental Neurobiology, in close collaboration with the Department of Computational Biology. The goal of the Developmental Neurobiology Department, led by Dr. Michael Dyer, an HHMI investigator, is to understand how neurons are formed during development and how that process can become deregulated in pediatric brain tumors.  Emphasis is placed on applying cutting edge computational approaches to some of the most innovative biological studies in the field. Members of the Department of Developmental Neurobiology publish in high profile journals including Nature, Cell, Science, Cancer Cell, Neuron, Nature Neuroscience, Nature Genetics, Cell Stem Cell and many others. The Computational Biology Department has a well-established track record in leading bioinformatics analysis for high-profile genomic and translational research projects such as the St. Jude/Washington University Pediatric Cancer Genome Project. Specific projects include the integrative analysis of ChIP-seq of histone marks and transcription factors, ATAC-seq, Hi-C, Capture-seq, whole-genome and whole exome sequencing, whole transcriptome RNA-seq data to understand the mechanism of key molecular pathways involved in tumorigenesis especially pediatric brain and solid tumors. Candidates with an understanding of epigenomics, clonal analysis and single cell RNA sequencing analysis and with strong problem solving skills, attention to detail, critical thinking, and expertise in next-generation sequencing data analysis are highly encouraged to apply for this position.

Responsibilities

Minimum Experience

  • Ph.D which must include research related to bioinformatics (such as analysis of sequence data, microarrays, SNPs, image data, proteomics data, or biological pathways; development of algorithms, statistical methods, or scientific software); OR If Ph.D with no bioinformatics research, then two (2) years of pre-or postdoctoral experience in Computational Biology or Bioinformatics research is required
  • Experience with programming languages such as Perl, C, or Java required

Preferred Skills

  • Experience with Python and knowledge on statistical analysis package such as R and Matlab is highly desired. Experience in epigenetics analysis such as ChIP-seq, ATAC-seq, HiC, WGBS, RNA-seq, single cell sequencing is preferred. Knowledge about neurobiology is also a plus.

Minimum Education

  • Ph.D. in Molecular Biology, Biochemistry, Computer Science, Statistics, Mathematics, Bioinformatics or related field required
  • Ph.D. which must include research related to bioinformatics (such as analysis of sequence data, microarrays, SNPs, image data, proteomics data, or biological pathways; development of algorithms, statistical methods, or scientific software).
  • OR
  • If Ph.D. with no bioinformatics research, then two (2) years of pre-or postdoctoral experience in Computational Biology or Bioinformatics research is required

Ready to join a team that is always innovating, because we believe anything is possible?

Apply now at: http://bit.ly/2AiEBbv

St. Jude Children’s Research Hospital is an Equal Opportunity Employer. St. Jude does not discriminate on the basis of race, national origin, sex, genetic information, age, religion, disability, sexual orientation, gender identity, transgender status, veteran’s status or disabled veteran’s status with respect to employment opportunities.  All qualified applicants will be considered for employment.  St. Jude engages in affirmative action to increase employment opportunities for minorities, women, veterans and individuals with disabilities.