Post-Doctoral Research Fellow, B Cell Immunology and Vaccines
Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
The Stamatatos Lab, within the Vaccine and Infectious Disease Division of the Fred Hutchinson Cancer Research Center, focuses on developing immunization approaches to expand and guide the maturation of particular B cell lineages along specific evolutionary pathways that result in the production of protective antibodies against infectious agents. We employ a wide range of experimental approaches, including deep sequencing and bioinformatic analysis of B cell receptor repertoires, structure-based immunogen-design, immunological, molecular and cellular biology techniques, crystallography, and knock-in and transgenic animals. Our work includes the pre-clinical and clinical evaluation of candidate vaccines.
Our Lab is seeking outstanding Postdoctoral Fellows to work on developing and testing new immunogens and immunization protocols to guide the maturation of particular B cell clones along specific evolutionary pathways in animals and humans.
- Primary B cell analyses upon immunization of knock-in and transgenic mice
- Protein immunogen design, expression and characterization
- May involve use of Yeast-display approaches
- Initiate and carry out scientific projects, under the supervision of Dr. Stamatatos
- Develop and demonstrate a thorough understanding of the scientific literature relating to the research topics.
- Conduct and publish research in appropriate journals.
PhD in T or B cell immunology. Expertise in diverse immunochemical and molecular approaches is required. Additional expertise in Yeast-display approaches is a plus. The candidates must show initiative, willingness to take up new skills and responsibilities, and be a team player. Excellent attention to details and the ability to work independently are essential to success in this position, as are good communication and organizational skills. The candidates must be self-motivated, able to multitask and to work within a very collaborative environment. Salary will be commensurate with appropriate experience.
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