Postdoctoral Fellow | Leukemia Cell Survivial | Heisterkamp Lab
City of Hope, an innovative biomedical research, treatment and educational institution with over 5,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.
Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's 20 leading cancer centers that develops and institutes standards of care for cancer treatment.
PostdoctoralFellow | Leukemia Cell Survival | Heisterkamp Lab
Department of Systems Biology, Beckman Research Institute
Position Summary and Key Responsibilities:
Acute lymphoblastic leukemia develops in the bone marrow. The leukemia cells can become resistant to drug treatment because they obtain support for their growth and survival from stromal cells in this environment. Our lab studies the molecules and mechanisms that are responsible for this type of drug resistance development. For this position we are particularly interested in someone with a PhD and expertise in cell biology to study mechanisms of lysosomal programmed cell death. We work with leukemia in tissue co-culture with stromal cells, cell imaging, retroviral or lentiviral transduction, Cas/CRISPR knockout, FACS, and mice. Candidates who are interested in following an academic career path, are self-motivated and enjoy the complexity of biological systems are especially encouraged to apply.
Minimum Education and Skills Required for Consideration:
We are in particular looking for someone with a PhD in cell biology. The project involves working with hematopoietic cells in tissue culture, imaging cells. Expertise in glycobiology is an advantage but not required.
How to apply: Please include an updated CV, a 1-page cover letter describing your current position, your reasons for applying and contact details of three recent referees as a single PDF.
The location of our lab at the Monrovia Campus of the Beckman Research Institute within the Department of Systems Biology provides many opportunities to interact with others who study leukemias. Our lab also has ongoing collaborations in the area of glycobiology with scientists at the Institute for Glycomics, Griffith University, Australia.
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.