About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 5,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.
Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's 20 leading cancer centers that develops and institutes standards of care for cancer treatment.
Position Summary and Key Responsibilities:
Develops an independent, NIH-funded research program in the field of hematological malignancies, including acute myeloid leukemia, acute lymphoblastic leukemia and B cell lymphoma, leads a research group of postdoctoral scientists, provides mentorship and scientific guidance, oversees experimental studies in his/her laboratory, publishes high-quality research manuscripts, develops research grant proposals for consideration by NIH and other peer-reviewed funding agencies. Performs original research in the Department of Systems Biology.
The following are essential job accountabilities:
Research: Perform original research including the role of oncogenic signal transduction, metabolism and aberrant regulation of transcription in acute leukemias and B cell lymphoma.
- Implement genetic mouse models for leukemia and lymphoma
- Develop cutting-edge methodologies in gene editing, transcriptional regulation (inducible dCas9 regulators), computational biology tools.
- Contribute new ideas, actively engage in scientific discussion, provide expertise to inform discussion of new concepts
- Contribute to department meetings and research conferences
- Supervision of post-doctoral fellows and technologists as relevant for research activities.
- Write original scientific manuscripts.
- Review scientific manuscripts and grant applications
- Contribute and assist in grant applications.
- Contribute to quality controls, verification of scientific results, rigor and robustness of scientific data by mentoring junior members of the Department.
- Contribute to good record keeping, archiving of primary research data, assist with implementation of digital laboratory note books that can be shared among all members of the group, contribute to building and maintenance of a shared file server structure.
- Act as role model and contribute to good experimental practice, SOPs, laboratory safety and animal welfare.
- Participate in teaching activities of the Department and the Graduate School.
- Attend scientific conferences and present work of the group.
- Develops an independent, NIH-funded research program in the field of hematological malignancies, including acute myeloid leukemia, acute lymphoblastic leukemia and B cell lymphoma, which is based on multiple peer-reviewed research grants. [1 ], 
Leads a group of postdoctoral scientists, provides mentorship and scientific guidance, oversees experimental studies in his/her laboratory.
Publishes high-quality research manuscripts, develops multiple research grant proposals for consideration by NIH and other peer-reviewed funding agencies. , 
Collaborates with department personnel on research projects. Attends departmental meetings as required and participates in the department continuing education program.
Gives presentations of collaborative and methodological research at professional meetings and at invited seminars. , 
Enhances professional growth and development through participation in educational programs, reviewing current literature, attending service meetings, and workshops. Maintains professional growth and development through seminars, workshops, and professional affiliations to maintain certification/licensure, and/or keep abreast of latest trends in field of expertise.
Attends meetings as required. 
Performs other related duties as assigned or requested.
The following job accountabilities may be reassigned:
Assists in care and maintenance of laboratory work area and furnishings/equipment.
Minimum Education and Skills Required for Consideration:
MD degree and/or Ph.D. degree in Biology or related field of science
Five years in Molecular or Cell Biology
Experience in the biology of leukemia and lymphoma
Preferred Field of Expertise
Molecular and cell biology, immunology, B cell malignancies, cancer biology
Work independently. Foster and promote a positive image and professional appearance.
Computer peripheral equipment
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.