Clinical Genome Analyst

St. Jude Children’s Research Hospital
Memphis, Tennessee
January 31 2018
Life Sciences, Genomics
Organization Type

The World’s Brightest Minds Always Innovate

At St. Jude Children’s Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That’s why we provide world-class facilities. State-of-the-art technologies. Extraordinary support. And a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve. Quite simply, at St. Jude, we encourage you to dream big, and we give you everything you need to be the force behind our cures.

Clinical Genome Analyst

Memphis, TN

The department of Computational Biology is seeking a highly motivated scientist to join our Clinical Cancer Genomics team. As a clinical genome analyst, you will analyze and classify somatic and germline genetic alterations in pediatric cancer patients ascertained from whole-genome, whole-exome and transcriptome sequencing and present findings to pathologists, oncologists, and genetic counselors. This scientist will work closely with our bioinformatics pipeline and visualization teams to explore novel analysis approaches that aid molecular classification and clinical reporting, contribute ideas to automate and improve existing analysis methods, and assist in preparing and submitting manuscripts. The successful candidate will also have opportunities to participate in research projects to analyze the pediatric cancer genome and epigenome.


Our ideal candidate has a deep understanding of cancer biology and expertise in genomic and/or transcriptomic data analysis either through NGS or molecular pathology approaches. Prior experience within in a clinical environment and experience in clinical test development are highly desirable.

Recognized as a world leader in mapping the genetic landscape of pediatric cancers, the St. Jude department of Computational Biology has developed state-of-art computational infrastructure, well-established analytical pipelines, and deep genomic analysis expertise with a track record of high-impact publications in top-tier biomedical journals such as Nature, NEJM, JAMA, Nature Genetics and Nature Methods. The department provides a highly interactive environment with collaborative opportunities across basic and clinical departments, access to high performance computing clusters, cloud computing environment, innovative visualization tools, highly automated analytical pipelines and mentorship from faculty scientists with deep experience in data analysis, data management and delivery of high-quality results for highly competitive projects. This position is located in Memphis, TN, and relocation assistance is available. 

Minimum Education

PhD in Molecular Biology, Biochemistry, Computer Science, Bioinformatics or related field required. PhD in a field directly related to cancer biology with a strong desire to work in a clinical environment preferred.

Minimum Experience

PhD in Molecular Biology, Biochemistry, Computer Science, Bioinformatics or related field required. Prior experience must include research related to bioinformatics (such as analysis of DNA and RNA sequence data, microarray, SNPs, proteomics data, or biological pathways; development of algorithms, statistical methods, or scientific software).


If PhD training did not include bioinformatics research, will require a minimum of two (2) years of pre- or postdoctoral research experience in Computational Biology or Bioinformatics.

Experience with programming languages such as Perl, C, Python, Java, or R required.

Job Preferences: PhD in a field directly related to cancer biology with a strong desire to work in a clinical environment AND experience with programming languages.

Candidates at varying levels of their career will be considered.

Ready to join a team that is always innovating, because we believe anything is possible?

Apply now at:

St. Jude Children’s Research Hospital is an Equal Opportunity Employer. St. Jude does not discriminate on the basis of race, national origin, sex, genetic information, age, religion, disability, sexual orientation, gender identity, transgender status, veteran’s status or disabled veteran’s status with respect to employment opportunities.  All qualified applicants will be considered for employment.  St. Jude engages in affirmative action to increase employment opportunities for minorities, women, veterans and individuals with disabilities.