Post Doctoral Research Associate
University of North Dakota, PostDoctoral Research Associate, Position #16542
College of Arts & Sciences: Biology Department
The Biology Department at the University of North Dakota seeks a Postdoctoral Research Associate to study gene regulatory networks directing cell-fate decisions during hematopoiesis in an NSF-supported project. The appointment will be full-time and benefitted.
The Postdoctoral Research Associate is a joint position between the laboratories of Dr. Manu (Department of Biology; http://arts-sciences.und.edu/biology/faculty/manu.cfm) and Dr. Loh (Department of Physics; http://arts-sciences.und.edu/physics-astrophysics/loh/). We utilize tightly coupled experimental and computational approaches to uncover the gene regulatory logic underlying the differentiation of stem/multipotential progenitor cells into alternative lineages. Time resolved readouts of gene state, such as genome-wide gene expression, enhancer activity, and chromatin accessibility, are employed to constrain predictive mathematical models of gene regulation. Ongoing projects vary in scope from detailed cis-regulatory analyses of individual genes to broader studies of networks composed of dozens of genes. Our ultimate goal is to decode and model the regulatory logic of cell-fate decisions comprehensively, allowing the de novo prediction of gene expression dynamics in both normal development and reprogramming experiments.
The University of North Dakota has a vibrant and collaborative developmental biology and epigenetics community. The Manu lab is closely associated with an NIH funded Center for Biomedical Research Excellence focused on the epigenetics of development and disease (http://www.med.und.edu/epigenetics/) hosted at the University of North Dakota. We also collaborate with several labs in the School of Medicine and Health Sciences (SMHS). The Department of Biology and SMHS feature modern molecular biology and functional genomics facilities. The Manu lab has a dedicated 96-CPU high performance computing cluster.
Duties & Responsibilities
The Postdoctoral Research Associate will have the opportunity to work with a highly collaborative and multidisciplinary team developing novel approaches for inferring, modeling, and validating gene regulatory networks. We seek an independent experimental biologist with a strong interest in developmental biology and gene regulation and the ability to work collaboratively with other experimentalists and computational scientists. The postdoc will develop and implement projects, utilizing modern genome engineering and high-throughput sequencing approaches, to perturb gene networks for inferring their structure and expression dynamics. The postdoc will work closely with computational scientists to develop and validate mathematical models and will have the opportunity to learn computational techniques. The postdoc will disseminate the results of their work in the form of manuscripts and conference presentations. Successful candidates will be expected to mentor undergraduate and graduate students and interact with the larger developmental biology and epigenetics community at the University of North Dakota.
- PhD in a developmental, molecular, cellular biology or related field. Candidates with PhDs in quantitative fields will also be considered provided they have significant wet lab experience in genetics and molecular biology
- Experience in developmental genetics and molecular biology
- Experience with genome engineering techniques and/or functional genomics
- Experience with bioinformatics/computational biology
- Strong record of scholarly publications
To Apply: Please submit cover letter, CV, and contact information for a minimum of three references. Full consideration will be given to applications received by February 15, 2018.
If you have any questions, please contact Manu at firstname.lastname@example.org
All applicants must apply here: https://und.edu/finance-operations/human-resources-payroll/careers/secure/job-openings-external.cfm Position #16542; JobID: 4067
In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the US and to complete the required employment eligibility verification form upon hire.
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