Computational Senior Research Scientist in Systems and Synthetic Biology at NYU School of Medicine

Manhattan, New York City, New York
Salary will be commensurate with accomplishment, fit, and experience.
January 22 2018
Bioinformatic Management
Position Type
Full Time
Organization Type

Computational Senior Research Scientist/Postdoc in Systems Genetics at NYU.

Position available for a Senior Research Scientist or Postdoctoral Researcher with strong computational skills. The Noyes lab ( is growing and as we expand our work we need a strong computationalist to handle initial data analysis, expand on our approach, and to better interface with our collaborators. As students join the lab with computational interests, this person will be relied upon to mentor these students for their computational tasks. I am looking for someone to take the lead on the bioinformatic side of our research.

The Noyes lab in the Institute for Systems Genetics at the NYU School of Medicine is looking to build a team of exciting young scientists to scale up our understanding of protein interacts. At the heart of what we do is understanding the nuts and bolts of the molecular interactions between proteins and their targets. Our ultimate goals are first to characterize these interactions, the influence of genetic variation, and the connection to phenotype; but we also want to use this information to develop molecular, therapeutic tools that manipulate these interactions and the genomes that harbor them. We have already begun to put together a talented group and have been awarded funding from the NIH to support these projects. Our general focus can be summed by these themes:

  • Understanding how proteins determine target preference, with particular interest in low affinity interactions.
  • Describing the influence genomic variation has on protein function.
  • The development of novel genome manipulating tools (CRISPR, ZFN, pathway inhibitors) for precise applications such as therapeutic gene repair and cancer suppression.


MD or PhD. Established a record of publications

Candidates will have extensive experience dealing with large data sets, primarily recovered by next-generation sequencing. An understanding of protein function at the structural level is highly desirable. While extensive wet bench experience is not necessary, it would be helpful. If nothing else, candidates that desire to learn this side of the research will have an advantage. Therefore, experience working with either bacteria and human tissue cultures, cloning, genome editing, protein/nucleic acid library design as well as familiarity with common modes of protein-DNA, protein-RNA or protein-protein interactions, would be desirable but again, not required.

Interested applicants should submit a cover letter, CV, and a one page “Research Statement” describing their research accomplishments and goals and how those align with the requirements of the position. Application materials should be sent to

Salary will be commensurate with accomplishment, fit, and experience.

EOE including Disabled and Vets VEVRAA Federal Contractor


Institute for Systems Genetics

Alexandria Center for Life Science – West Tower, 5th floor

430 East 29th Street, New York, NY 10016

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