Postdoctoral Research Fellow – Microbiome Informatics Research

Employer
Merck
Location
Boston, MA, US
Posted
January 19 2018
Organization Type
Pharma
Requisition ID: POS000235

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its legacy for over a century. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.
Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases. 
Be a part of the legacy: MRL Postdoctoral Research Fellow Program The Merck Research Laboratories (MRL) Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.
Position Overview: 
As a postdoctoral fellow in Microbiome Informatics Research at Merck Research Laboratories (MRL) and the Merck Exploratory Science Center (ESC), you will work with a highly collaborative team of scientists at the interface of microbiology, chemical biology, pharmacology, and machine learning.  An unprecedented set of microbiome metabolism data will be generated, and used to characterize specific bacterial proteins, strains of bacteria, and bacterial communities.  The outcome of the postdoc will be a deeper understanding of the functional role the microbiome plays in diseased and healthy individuals, as well as of the impact of the microbiome on drug and hormone metabolism. Responsibilities include but are not limited to:
  • election of compounds for metabolism study
  • Execution of limited experimental studies related to the transformation of small molecules by bacterial entities
  • Statistical and machine learning analyses of metabolism data

Qualifications

Education Minimum Requirement:  
  •  PhD in Chemistry, Chemical Biology, Biochemistry, Bioinformatics, Microbiology, Computational Biology, Pharmacology, Computer Science, Machine Learning, or a related field with less than 3 years of Postdoctoral Experience or achieved a  Ph.d by Spring/Summer of  2018 

Required Experience and Skills:
  • Demonstrated proficiency in data-mining or statistical modeling methods
  • Familiarity with wet-lab experimentation (this might include in vitro testing, cell-based assays, bacterial cultivation, sterile techniques)
  • Experience with interpreting wet-lab data (this might include phenotypic screens, LC-MS data, pharmacology data)
 Preferred Experience and Skills:
  • Familiarity with cheminformatics (QSAR models, metabolism prediction)
  • Familiarity with bioinformatics
  • Computational skills (e.g., Pipeline Pilot, Python, Perl, R, Matlab, SQL, etc.)
  • Track record of innovative research combining methods from multiple disciplines to solve complex problems
  • Strong history of publication in peer-reviewed journals

Our employees are the key to our company’s success.  We demonstrate our commitment to our employees by offering a competitive and valuable rewards program.  Merck’s benefits are designed to support the wide range of goals, needs and lifestyles of our employees, and many of the people that matter the most in their lives. Merck is an equal opportunity employer, M/F/D/V – proudly embracing diversity in all of its manifestations. Former Military, Transitioning Service Members, National Guard & Reserves - We value your past and present service
mrlpostdoc

Job: Post-Doctoral Fellow
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Employee Status: Regular
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Company Trade Name: Merck