Sr. Research Associate, Potency Assay Development

December 21 2017
Life Sciences, Biology
Organization Type
Sr. Research Associate, Potency Assay Development

Position Summary

Moderna is seeking a highly skilled, talented and motivated in vitro analyst for a position based at their Cambridge, MA site.  The individual will participate in the development and performance of cellular and biochemical potency assays to support advancement of Moderna's mRNA clinical development candidates.


  • Development and performance of in vitro assays (ELISA, FACS, Western blotting, luminescence, functional activity) using cultured and primary mammalian cells to support product development
  • Transfer of potency assays to CRO/QC laboratory for qualification and validation, for release and stability testing under GMP
  • Standard mammalian cell culture support including maintaining and plating of cell lines
  • General laboratory assistance including lab equipment maintenance, preparation of reagents, and the ordering and receiving of lab supplies
  • Closely collaborate with members of the In Vitro Biology, Technical Development and Quality Control teams, and broadly with R&D departments throughout the company
  • Accountable for experiment design, success and results delivery
  • Record and communicate findings
  • Presentation of results at internal meetings


  • BS with 2-5 years of industry experience, or MS with 0-2 years of industry experience (Cell Biology, Biochemistry, Molecular Biology, or related science), developing and performing cellular and biochemical assays, preferably in a GMP environment
  • Hands on experience with mammalian cell culture and the utilization of cell-based assays to examine the expression and activity of a variety of protein targets
  • Significant experience in ELISA assay development and performance
  • Excellent interpersonal, organizational, and collaborative skills, attentive to detail, and the ability to work independently and effectively in a highly dynamic environment
  • Preferred: Familiarity with the regulatory landscape and government agency guidance for potency assay development, qualification and validation
  • Preferred: Familiarity with nucleic acid therapeutic characterization
  • Preferred: Ability to multi-task to meet aggressive timelines and development goals


Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

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