Principal Scientist, Cardiovascular Research

South San Francisco, CA, US
November 16 2017
Organization Type
Requisition ID: RES002026

Merck Research Laboratories South San Francisco, a wholly owned subsidiary of Merck and Co., is focused on driving discovery research.  Our new multi-disciplinary discovery research site offers state-of- the-art resources to explore the most promising science combined with Merck’s world-class R&D expertise in small molecules and biologics. Located within the heart of the Bay area’s biomedical community, research conducted in our new laboratories spans exploratory biology through early clinical development and is an integral part of Merck’s powerful world-class network of drug and vaccine discovery.  Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of an individual like you.  To this end, we strive to create a fast-paced, nimble and flexible environment of mutual respect, creativity, invention and teamwork.  With access to Merck’s proven global R&D organization, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career. This is an outstanding opportunity for a highly motivated, experienced, innovative Principal Scientist with a strong background in the area of Cardiovascular to join the research team focused on novel drug discovery at Merck Research Laboratories at our new site in South San Francisco, CA. Here you will be able to participate in a vibrant culture of world leading academic and biotech research centers. Beyond local connections, you will also be able to supplement your research activities by taking advantage of the technologies and capabilities of the wider Merck network of sites in Boston, MA as well as NJ and PA.

Responsibilities include and are not limited to the following:
  • Expected to promote and facilitate creative thinking from target identification/validation through lead optimization and preclinical support of clinical programs. An important aspect will be helping to drive innovative translational strategies from preclinical in vitro and/or in vivo models to human clinical research
  • Be a “drug creator”, and promote such thinking within the team and, by influence, your colleagues in other disciplines with whom you will work closely
  • Strong communication skills will be required to influence both cross-site therapy area aligned groups as well as functional area disciplines
  • Ability to balance internal cross-site activities with an expansive program of collaborative research with leading laboratories in the external scientific community to drive innovation and a deeper understanding of human biology resulting in the discovery of novel targets in CMD
  • Responsible for contributing to CMD area strategy in collaboration with senior management and play a lead scientist role on Scientific Review and Licensing committees
  • Provide program leadership
  • Promote Merck externally in the scientific and business communities
  • Maintain high visibility among internal and external peers
  • Participate in hiring outstanding scientists in the CMD area
  • Participate in the leadership forums at the local site with other functional leaders. As this is a new site, it will be important that you help to shape the culture beyond the science
  • Strong team player with excellent oral and written communication skills
  • Demonstrated ability to lead cross-functional project teams
  • Motivate, influence, and develop & coach others will be essential in this role
  • Expected to encourage innovative thinking and risk taking, while eliminating obstacles and barriers in order to implement change
  • Ability to present clear and compelling scientific and business cases will be important

  • Required: Ph.D.
Required Experience:
  • Minimum of (8) years Industry experience, preferably in Cardiovascular, or a related area OR minimum of (10) years experience in Academia with a strong Cardiovascular background
  • Hands-on experience in ex-vivo and in vivo cardiovascular skills and willing to work in the lab
  • Experience in the disease area of Heart Failure and/or Pulmonary Hypertension
  • Ability to present a clear and compelling scientific case
  • Proven track record in academic basic science training
Preferred Experience:

  • Strong knowledge of drug discovery and development
  • Experience in Atherosclerosis and Vascular Biology
 The quality of our team is essential to our success. We are creating a new and innovative approach to rewarding our employees and establishing a comprehensive value proposition. Our competitive compensation program and benefits are designed to support the wide range of goals, needs and lifestyles of our employees, and the people that matter the most in their lives. If you need an accommodation for the application process please email us at  Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products.  Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for us all.

Job: Research Science
Other Locations:
Employee Status: Regular
Travel: Yes, 5 % of the Time
Number of Openings:
Shift (if applicable):
Hazardous Materials:
Company Trade Name: Merck

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