Cellular Bioenergetics in Neurodegenerative Diseases: A system-based pathway and target analysis ...

Employer
Università degli Studi di Padova - Dipartimento di Scienze Biomediche
Location
Italy
Posted
October 12 2017
Position Type
Full Time
Organization Type
Academia

The project is based on a systems-based target analysis to determine the contribution of mitochondria and cell bioenergetics to disease progression in three common neurodegenerative disorders: Parkinson's disease (PD), Alzheimer's disease (AD) and Huntington's disease (HD). Specific aims will be: i) elucidate common and distinct disease mechanisms in AD, PD and HD focusing on pathways regulating mitochondrial functions and cell bioenergetics; ii) employ computational modelling frameworks and a HTS approach to identify drug candidates and therapeutic targets



This job comes from a partnership with Science Magazine and Euraxess