Doctoral student in organic chemistry

Employer
Lund University
Location
Sweden
Posted
October 12 2017
Position Type
Full Time
Organization Type
Academia

H2020-MSCA-ITN-2017-EJD: Marie Sklodowska- Curie Innovative Training Networks (European Joint Doctorate)


Grant agreement nº: 765581 


PhD position in organic chemistry within carbohydrate medicinal chemistry. 


Project title: ESR11 - Discovery of inhibitors of bacterial sialic acid sodium solute symporters. 


An Early Stage Researcher position (PhD studentship) is available for 36 months from January 2018 within the European Training Network PhD4GlycoDrug (http://www.phd4glycodrug.eu). 


PhD4GlycoDrug is a multidisciplinary Innovative Training Network - European Joint Doctorate funded by the European Commission under the Horizon 2020 Marie Sklodowska-Curie Action. The project brings together 12 groups from academia and the private sector to address scientific challenges in discovery and development of drugs interfering with glycobiological life processes (Glyco Drugs). 


The fellow will be performing her/his PhD thesis work at the Department of Chemistry of Lund University, Sweden, under the supervision of Professor Ulf Ellervik and at the Department of Pharmaceutical Sciences of the University of Basel, Switzerland under the supervision of PD Dr. Oliver Schwardt. 


Description 


The research project is to design and synthesize new chemical entities as high-affinity, selective, orally available inhibitors of bacterial sialic acid symporter proteins with optimized PK-ADMET properties. Knowledge-based design based on published structures, as well as de novo design, will be the basis for selecting synthetic target molecules. 


The selected candidate will participate in the network's training activities and work placements in the laboratories of the participating academic and industrial teams. Regular meetings and workshops within the EU-funded PhD4GlyoDrug International Training Network-European Joint Doctorate will complement the training and support provided by the host institutions. 


Work duties


The main duties of doctoral students are to devote themselves to their research studies which includes participating in research projects and third cycle courses. The work duties can also include teaching and other departmental duties (no more than 20%). 


Admission requirements 


A person meets the general admission requirements for third-cycle courses and study programmes if he or she:


 


has been awarded a second-cycle qualification, orhas satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the second cycle, orhas acquired substantially equivalent knowledge in some other way in Sweden or abroad. A person meets the specific admission requirements for third cycle studies in organic chemistry if he or she has: 


at least 120 credits in chemistrya thesis work of at least 30 credits on an advanced level in organic chemistryAdditional requirements 


completed their M.Sc. or equivalent and have not acquired, since, more than 4 years (full-time equivalent) research experience.passed a course in advanced theoretical organic chemistry (or equivalent)passed a course in advanced practical organic chemistry (or equivalent)excellent knowledge of the English language (spoken and written / proficiency level). Assessment criteria 


Selection for third-cycle studies is based on the student's potential to profit from such studies. The assessment of potential is made primarily on the basis of academic results from the first and second cycle. Special attention is paid to the following: 


Knowledge and skills relevant to the thesis project and the subject of study. An assessment of ability to work independently and to formulate and tackle research problems. Written and oral communication skills Other experience relevant to the third-cycle studies, e.g. professional experience. Other assessment criteria: 


practical experience of carbohydrate chemistrypractical experience of medicinal chemistrypractical experience of studying carbohydrate-protein interactionspractical experience of analytical methods (LCMS, NMR, HPLC, IR)letters of recommendation from relevant persons/institutionsinternational experience (studying, internship or research work abroad for a period of at least 1 month). Consideration will also be given to good collaborative skills, drive and independence, and how the applicant, through his or her experience and skills, is deemed to have the abilities necessary for successfully completing the third cycle programme. 


At the time of recruitment, the successful candidate must not have been awarded the doctorate degree and must not have resided, nor carried out their main activity (work, studies, etc.) in Sweden or Slovenia for more than 12 months in the 3 years immediately prior to the first day of employment. 


Terms of employment 


Only those admitted to third cycle studies may be appointed to a doctoral studentship. Third cycle studies at Lund University Science faculty consist of full-time studies for 4 years. A doctoral studentship is a fixed-term employment of a maximum of 5 years (including 20% departmental duties). Doctoral studentships are regulated in the Higher Education Ordinance (1993:100), chapter 5, 1-7 §§. 


Benefits 


Salary and other benefits are according to EU-standards for Marie Sklodowska-Curie Actions and national regulations. Additional benefits are foreseen in case of family allowances. 


Instructions on how to apply 


Applications shall be written in English and include a cover letter stating the reasons why you are interested in the position and in what way the research project corresponds to your interests and educational background. The application must also contain a CV, degree certificate or equivalent, and other documents you wish to be considered.


Motivation letter and Statement of purposeCurriculum vitaeReferences (at least three)Certificates evidencing met eligibility criteriaStatement evidencing met mobility criteriaSummary of a research article; verification of candidate skills in terms of understanding and analysing science, understanding and writing in English language (article available here: http://un-nas.chem.lu.se:15409/sharing/ISODqS3mc)


The summary should consist of 2000-2500 characters, one figure, and fully referenced. The deadline for application is 15th November 2017 and the application should reference “PhD4GlycoDrugs - EJD - ESR11”. 


The results will be published at http://www.phd4glycodrug.eu/positions/.

Eligibility

Students with basic eligibility for third-cycle studies are those who- have completed a second-cycle degree- have completed courses of at least 240 credits, of which at least 60 credits are from second-cycle courses, or- have acquired largely equivalent knowledge in some other way, in Sweden or abroad.


The employment of doctoral students is regulated in the Swedish Code of Statues 1998: 80. Only those who are or have been admitted to PhD-studies may be appointed to doctoral studentships. When an appointment to a doctoral studentship is made, the ability of the student to benefit from PhD-studies shall primarily be taken into account. In addition to devoting themselves to their studies, those appointed to doctoral studentships may be required to work with educational tasks, research and administration, in accordance with specific regulations in the ordinance.


Type of employment

Limit of tenure, four years according to HF 5 kap 7§.


Contacts:

- Ulf Nilsson, professor, 046-222 82 18; ulf.nilssonatchem.lu.se

- Ulf Ellervik, professor, 046-222 82 20; ulf.ellervikatchem.lu.se



This job comes from a partnership with Science Magazine and Euraxess