Senior Scientist, Computational Chemistry Job

Employer
Merck
Location
Kenilworth, NJ, US
Posted
October 12 2017
Organization Type
Pharma
Requisition ID: CHE005570

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its legacy for over a century. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.



Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases. 




The Modeling and Informatics group is seeking a creative, self-motivated computational chemist with exceptional interpersonal and problem solving skills to join our scientific team in Kenilworth, NJ.





The successful candidate will be responsible for the design and optimization of novel drug candidates using advanced computational techniques, with a particular focus on integrating chemical biology, ligand- and knowledge-based methods into compound and target prioritization. In addition to participating in the support of Merck’s medicinal chemistry programs, the applicant will be expected to continue research in new areas of molecular modeling relevant to the drug discovery and development process.



Qualifications

Education: 




  • Ph.D. (or expected in next 3 months) in chemistry, biochemistry, biophysics or chemical biology a computational emphasis


Required: 




  • Strong communication skills

  • The ability to work well in multidisciplinary teams

  • Evidence of creative application of computational approaches to problems of pharmaceutical interest

  • Evidence of integration of chemical biology, target or SAR knowledge into computational design


Preferred:




  • Track record of publications, posters, and speaking engagements

  • Experience or solid understanding of one or more of biological assays, ADME or PK/PD and their application in drug discovery

  • Experience in modern molecular modeling techniques (docking, molecular simulation, homology modeling, pharmacophore modeling, quantum mechanics, statistics, QSAR, QSPR, ligand- and structure-based design) 

  • Experience with modern software packages (Schrodinger, OpenEye, CCG)

  • Experience in scientific programming (Perl, Python, Pipeline Pilot) and/or data analytics (Spotfire).




Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life. 


 


If you need an accommodation for the application process please email us at staffingaadar@merck.com.


  


Search Firm Representatives Please Read Carefully: 


Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity.  Please, no phone calls or emails.  All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck.  No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.


 


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Job: Chemistry
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Employee Status: Regular
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Company Trade Name: Merck