EXPERT IN LARGE BIOLOGICAL MOLECULE ANALYSIS / PHARMACOKINETICS

Employer
SERVIER MONDE
Location
Orléans (Arrondissement), Loiret (FR)
Salary
up to 50,000 € environ per year
Posted
October 11 2017
Ref
794
Position Type
Full Time
Organization Type
Pharma

OUR COMPANY – GENERAL OVERVIEW

Servier is an international pharmaceutical company governed by a non-profit Foundation and headquartered in France.

With a strong international presence in 148 countries and a turnover of 4 billion euros in 2016, we employ over 21,000 people worldwide.

Being completely independent, we reinvest 25% of turnover (excluding generics) in Research and Development and use all our profits in growth.

We are specialised and driven by our constant search for innovation in five major research areas: cardiovascular diseases, cancers, diabetes, immuno-inflammatory diseases and neurodegenerative diseases, as well as by our activities in high-quality generic drugs.

Currently, we have 23 drug candidates including 19 new molecular entities at various stages of clinical development.

Our priorities are pathologies with high medical needs within our areas of expertise.

Therapeutic Areas

Cancers

Becoming a key player in oncology is part of Servier’s long-term strategy. Currently, there are nine molecular entities in clinical development in this area, targeting gastric and lung cancers and other solid tumors, as well as various leukemias and lymphomas. This portfolio of innovative cancer treatments is being developed with partners worldwide, and covers different cancer hallmarks and modalities, including cytotoxics, proapoptotics, targeted, immune and cellular therapies, to deliver life-changing medicines to patients.

Immune-inflammatory diseases

Becoming a key player in the fight against immune-inflammatory diseases is part of Servier’s long-term strategy. Servier wishes to bring innovative therapeutic solutions to patients suffering from these pathologies, which are often highly debilitating. Its research focuses on lupus, Gougerot-Sjögren syndrome and scleroderma, for which there is no cure.

This goal will be reached by establishing partnerships worldwide, to contribute to the speeding up of marketing of innovative drugs with high added value for patients.

Neurodegenerative diseases

Servier has a solid commitment to neuropsychiatry and to proposing innovative therapies to patients suffering from neurological conditions. Its Research teams are investigating new ways to treat Alzheimer’s and Parkinson’s diseases, as well as a broad range of neurodegenerative disorders, by targeting the toxic proteins that lead to neuron death. The priority is on focusing on the causes of the diseases rather than their symptoms. Currently, there are 5 projects at different stages of research and development in this promising area. This portfolio of innovative treatments is being developed with academic and biotech partners worldwide.

Company Strategy & 2020 Goals

  • Increase Research output : launch on the market one new molecular entity every 3 years
  • Achieve sales of 5 billion Euros
  • Become a key player in oncology and reinforce the group’s presence in its historical therapeutic areas, especially cardiology.

EXPERT IN LARGE BIOLOGICAL MOLECULE ANALYSIS / PHARMACOKINETICS  

Contexte:  

Localisation géographique : Orléans,  Loiret (45) FRANCE

Hiérarchie :          HEAD OF BIOKINETICS DEPARTMENT–PHARMACOCINETIQUE RESEARCH AND DEVELOPMENT CENTER

    

PRINCIPALES RESPONSABILITES

We are seeking a highly motivated individual with a solid experience and knowledge of Pharmacokinetics of Large Biological Molecules, including bio-analysis and immunology concepts.

Having a strong background in Immunology, Pharmacokinetics and in large molecules characterization / quantification, you will be in charge of the design and management of pharmacokinetic studies involving large molecules (antibodies, drug conjugates, proteins and/or polypeptides).

You will be also responsible for the assessment of the immunogenicity strategy of our new biological entities, including immunoassay and/or mass spectrometry method development, with management of an experienced technical team in the field.

You will perform Pharmacokinetic interpretations in coordination with pharmacological teams, bio-analysis platform and discuss the results with the PK representative of project teams. You will be in charge of the scientific documentation of the studies (study plans, reports, brochures…).

As part of the future development of the group, you will evaluate and implement new tools and/or technologies to expand capabilities and enhance efficiency in the related fields. You will also work in accordance with the current Guidelines in the field.

The candidate should demonstrate technical proficiency, scientific creativity, teamwork and excellent verbal and written skills (French & English), and is expected to be involved in the management of an experienced technical team.

PROFIL  IDEAL

The eligible candidate should have a PhD degree in Biology, Immunology, Pharmacy or related field, with a minimum of 3 years’ experience with demonstrated expertise in the areas of immunogenicity mechanisms, large molecules analysis and/or pharmacokinetics; in a pharmaceutical industry environment. As the position includes the management of a technical lab team, a recognized experience in management is required for this job, as well as excellent communication skills.

If you recognize yourself in this description and you feel ready to take this challenge, send us yourapplication , ref.794, to: katia.da-cruz@servier.com

Apply for EXPERT IN LARGE BIOLOGICAL MOLECULE ANALYSIS / PHARMACOKINETICS

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