PhD Characterizing cardiovascular patients and treatments using big data methods

University of Groningen
October 11 2017
Position Type
Full Time
Organization Type

The Groningen Research Institute of Pharmacy of the Faculty of Science and Engineering offers a scholarship PhD position for a talented and motivated national or international student.

Candidates are invited to write and develop their own research project within the scope of the proposed topic listed below. Being part of a cutting-edge research programme, they will receive excellent training in the form of hands-on instruction, advanced courses and summer/winterschools, complemented by workshops on generic research and transferable skills as well as teaching training. As a PhD candidate, you are committed to conduct independent and original scientific research, to report on this research in international publications and conference presentations, and to describe the results of the research in a PhD dissertation, to be completed within 4 years.

Parts of this project will be in close collaboration with the University College London and limited academic visits are encouraged.

Research topic
Due to successful public health measures and treatments, cardiovascular mortality has been greatly reduced in high-income countries. Clearly, patients with established cardiovascular disease are at an increased risk for disease progression, however patients differ in characteristics, (time to) disease progression or treatment response. During this PhD you will jointly use omics (genomics, and metabolomics) data and electronic healthcare record (EHR) data to 1) to classify patients at high risk for early cardiovascular disease progression, 2) identify markers for treatment response and 3) perform disease sub-phenotyping. Depending on the candidate's preference further possibilities include the evaluating and/or development of big data analytics.

This job comes from a partnership with Science Magazine and Euraxess