Research Scholar

Location
San Francisco, CA
Salary
Up to 58,560.00 + benefits based on experience
Posted
September 28 2017
Ref
17-0095
Position Type
Full Time
Organization Type
Non-Profit

The Research Scholar will take a leading role in the investigation of the immune mechanisms involved in susceptibility of patients with COPD to develop respiratory exacerbations.  

 

This clinical/translational research laboratory under the direction of Mehrdad Arjomandi, M.D. in the Division of Pulmonary & Critical Care is part of a multidisciplinary group at the San Francisco VA Medical Center with special focus on role of human macrophages and T-cells in respiratory diseases.

 

We are seeking a highly motivated and creative individual at the post-doctoral level, preferably with previous post-doctoral experience, to take a unique opportunity to lead the basic science aspect of an ongoing clinical/translational research project with direct human relevance.

 

Essential Functions:

  • Design and perform cell-culture based assays such as phagocytosis, efferocytosis, migration, adhesion, and wound-healing (scratch) tests.
  • Design and perform protocols using flow cytometry based assays.
  • Produce written reports detailing results of experiments and analysis of results; draft manuscripts of results for publication
  • Perform other molecular and cellular biological assays including:
    • Cell-based functional assays
    • Microscopy
    • Immunoblotting (western)
    • ELISA
    • RNA and DNA purification
    • PCR
  • Process, store, and perform lab-based assays on human biological samples.
  • Present oral and poster reports at monthly laboratory meetings, as well as national meetings
  • Assist with training of research methods and approaches to laboratory group
  • Assist with composition of grant applications
  • Perform other duties as assigned

Job Requirements:

  • Ph.D. in Immunology or related science or equivalent combination of education and experience.
  • Expertise with design and performance of flow cytometry based assays.
  • Expertise in flow cytometry software such as FlowJo.
  • Significant experience with primary cell cultures, specifically airway cells; experience with cell culture techniques including sterile techniques, maintenance of cell lines, freezing and thawing of samples
  • Experience with in vitro cell assays including migration, adhesion, and scratch assay
  • The following essential personal characteristics:
    • Detail-oriented and careful attention to detail; maintain a detailed laboratory notebook of experiments done on a daily basis
    • Ability to provide scientific troubleshooting of protocols and procedures
    • Adequate command of English language to be able to write scientific reports
    • Excellent organizational skills
    • Ability to meet deadlines
    • Demonstrate solid interpersonal skills
  • Experience with fluorescence microscopy
  • Experience with basic molecular biology techniques such as western blots, PCR, ELISA