Senior Scientist, Hybridomas & Assay Development Job

Palo Alto, CA, US
September 26 2017
Organization Type
Senior Scientist, Hybridomas & Assay Development-MOL000373


Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its legacy for over a century. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases.

We are seeking an experienced and highly motivated Senior Scientist to join the Antibody Generation group to contribute to Merck's Biologics unit in Palo Alto. Primary responsibilities will include the screening and characterization of antibodies to support antibody lead generation programs across multiple therapeutic areas.

The ideal candidate must have significant experience with molecular interactions and cell-based assay development utilizing multiple technologies. Previous experience screening antibodies (crude and purified) to characterize binding and functional activity is a must. The candidate will also support hybridoma generation (immunizations, fusions and screening) as needed.

The candidate is expected to be up-to-date on advanced technologies for screening platforms and actively apply new concepts as appropriate to continuously improve functional area capabilities.



- BA with a minimum of 7 years of related experience or a MS with a minimum of 4 years of related experience in cell biology, immunology, biochemistry or a related discipline of relevant experience


- Experience in high-throughput protein and cell-based assay development and screening in a pharmaceutical or biotechnology setting

- Experience generating hybridomas (immunization and fusion)

- Experience with cell culture

- Ability to manage multiple projects simultaneously

- Excellent written and verbal communication skills

- Excellent collaborative skills


- Experience working with Biacore and ForteBio Octet

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life.

If you need an accommodation for the application process please email us at

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Job: Molecular Discovery - Biologics

Job Title:Sr. Scientist, Molecular Discovery

Primary Location: NA-US-CA-Palo Alto

Employee Status: Regular

Travel: No

Number of Openings: 1

Shift (if applicable): N/A

Hazardous Materials: Standard lab chemicals

Company Trade Name:Merck

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