Postdoctoral Researcher in Precision Cancer Medicine

Employer
SciLifeLab
Location
Sweden
Salary
Fixed pay
Posted
September 25 2017
Position Type
Full Time
Organization Type
Academia

Postdoctoral Researcher in Precision Cancer Medicine  

At the Department of Oncology-Pathology basic, translational and clinical research and educational activities related to cancer is carried out. Approximately 300 people from over 40 nations are currently working at the department. 37 research groups with various cancer research profiles are involved and we have around 120 PhD students. The Department of Oncology-Pathology is responsible for undergraduate courses in Pathology, Oncology and Forensic Medicine for medical students, as well as for Tumor biology courses for biomedicine students and Pathology courses for opticians.

Research group Olli Kallioniemi
This position resides in the research group of Olli Kallioniemi, Director of Science for Life Laboratory, Professor of Molecular Precision Medicine, affiliated with both the Dept. Oncology and Pathology, Karolinska Institutet and the Science for Life Laboratory. The work will involve an exciting opportunity to practice precision cancer medicine research in a translational setting, with the aim to assign and optimize targeted treatments for individual cancer patients. Our disease focus is on acute myeloid leukemia (AML), ovarian and urological tumors (prostate, kidney and bladder). Our goal is to develop a systems biology framework to match targeted therapies and drug combinations using genomic, transcriptomic and proteomic profiling along with functional ex vivo drug testing on primary patient-derived cells from cancer patients. We work through team science in close collaboration not only with other research groups, but also with clinicians, as well as with different technology platforms at the SciLifeLab. For more information: https://www.scilifelab.se/researchers/olli-kallioniemi/.

Qualifications
The successful candidate is expected to have a doctoral degree in biochemistry, biology, genetics, biotechnology, medicine or other relevant field. The candidate should ideally have previous experience working as a post-doctoral researcher, be independent and motivated with a documented ability to carry out experimental research projects but also project management, including excellent communication skills in spoken and written English. Previous expertise in developing patient-derived models from solid tumors and/or hematological cancers is beneficial. Experience on high-throughput drug testing, assay development, high-throughput and high-content microscopy or -omics technologies and associated bioinformatics is highly valued. We value interest and experience in collaborative team science in a multidisciplinary environment.

Task Description
The tasks for this position involves the establishment of innovative drug testing assays in primary cell models, characterization of the models and integration of the datasets to predict the response of patients to drug therapy. The candidate is also expected to carry out project management tasks, such as carrying out expected milestones within the project, budgeting and reporting, as well as interacting not only with research but also clinical and pharma collaborators.

Desired qualification and experience
- PhD in biochemistry, biology, genetics, biotechnology, medicine or other relevant field
- Knowledge of cancer biology, precision cancer medicine and translational cancer research
- Experience in high-throughput drug testing and assay development
- Experience in working as part of large multidisciplinary, collaborative research projects (“team science”)
- Extensive experience in cell culture techniques, especially primary cell models

Application process, salary and contract
An application must contain the following documents in English: Curriculum vitae, qualifications and description of previous research and career plans, presented in accordance with Karolinska Institutet’s qualifications portfolio. For more information: http://ki.se/qualificationsportfolio. The application is to be submitted through the MyNetwork recruitment system. The salary is defined according to the KI salary system. The project is initially for two year contract with the possibility of extension with the preferred start date as soon as possible.

SciLifelab
Science for Life Laboratory (www.scilifelab.se) is a leading national infrastructure for next-generation life science research in Sweden. SciLifeLab is jointly operated by the four host universities: Karolinska Institutet, KTH Royal Institute of Technology, Stockholm University and Uppsala University, and it has facilities in four other universities across Sweden. There are over 1 000 people working at SciLifeLab, either in research groups or in the infrastructure facilities, most of them in the KI Solna campus and in Uppsala. Karolinska Institutet is one of the world´s leading medical universities. Its mission is to contribute to the improvement of human health through research and education. Karolinska Institutet accounts for over 40 per cent of the medical academic research conducted in Sweden and offers the country´s broadest range of education in medicine and health sciences. Since 1901 the Nobel Assembly at Karolinska Institutet has selected the Nobel laureates in Physiology or Medicine.

Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.

Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.

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Last application date: 19.Oct.2017 11:59 PM CET