Advanced software tools for data analysis of multi-well high-density MEA system.
The research is part of wider project for the development of a multi-well device for non-invasive in-vitro drug discovery. The tool will consist of 24 wells, each integrating the 3Brain's high-resolution chip featuring 4096 microsensors capable to record spiking activity from thousands of neurons. Wells will host neuronal networks obtained from human-derived iPS cells and forming a so-called “mini-brain”, a simplified model of the brain that can be studied to find treatments for neurodegenerative diseases. The current research package focuses on developing sophisticated software tools to acquire electrophysiological data from neurons and to provide statistical and data reduction methods that extrapolate meaningful information
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