Chronic kidney disease incidence in liver transplanted patients treated with tacrolimus or ciclos...

Università di Genova
September 21 2017
Position Type
Full Time
Organization Type

Immunosoppression of liver transplanted patients is based on tacrolimus or ciclosporin.

These drugs induce renal toxicity, expressed with acute or chronic damage, by mean of vasoconstriction.

Aim of the study is to evaluate, retrospectively, liver transplanted patients on immunosuppressive therapy with tacrolimus or ciclosporin these endpoints:

1) Evaluation of patient clinical characteristics;

2) Incidence of CKD at 6 months and at 1, 3, 5 years post a LT;

3) Comparison of CKD incidence related to eGFR respectively calculated by CKD-EPI and MDRD.

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