Engineering/Physics: Funded Joint PhD Studentship: Studying the visco-elastic behaviour of lymph ...

Employer
Swansea University
Location
Other
Posted
September 13 2017
Discipline
Other
Position Type
Full Time
Organization Type
Academia

This scholarship is for a joint Swansea-Grenoble PhD. During the candidature the successful applicant will spend time at the College of Engineering, Swansea University and the Doctoral School of Physics, at Université Grenoble Alpes.


Start date: 1 January 2018


Project description:


The lymphatic system returns fluid from interstitial spaces to the blood circulation and it serves as an important transport route for immune cells and antigens. Transport phenomena and/or breakdowns in lymphatic system performance are crucial in cardiovascular diseases, cancer, obesity, inflammatory diseases and injury resolution. However, little is actually known about transport mechanisms in this obscure system. In this project the rheological behaviour of lymph will be investigated and its effect on transport through the lymphatic system will be identified. Due to the small amounts of lymph available a micro-fluidic approach will be taken from design, fabrication, measurement, analysis to simulation of an actively pumping lymphatic network.


Objectives:


  • To design and fabricate a small-volume micro-fluidic rheometric device.

  • To interpret measurement data using computational models.

  • To identify the effect of lymph mechanics through computational models of the lymphatic system.

Supervisors:


  • Dr R. van Loon, Dr D.J. Curtis, Prof O.J. Guy, College of Engineering, Swansea University

  • Dr M. Ismail, Dr T. Podgorski Dept. of Physics, Communauté Universités Grenoble Alpe



This job comes from a partnership with Science Magazine and Euraxess