ERC H2020 Funded Biomaterials Postdoc Position

Employer
RCSI - Royal College of Surgeons in Ireland
Location
Europe
Posted
September 11 2017
Discipline
Other
Position Type
Full Time
Organization Type
Academia

Supervisor name: Dr Cathal Kearney,


Department Anatomy


Funding Agency European Research Council (ERC) - Horizon2020 Starting Grant


Postdoc Details Salary: €36,488


Start Date: Oct 2017


Subject Area (On-demand) drug/gene delivery; tissue engineering; biomaterial scaffold design; diabetic foot ulcers


Title of the Project Development of a Biomaterial Platform for On-Demand Delivery to Diabetic Foot Ulcers


Project Description


Although many skin wounds heal with conservative treatments, larger skin wounds or chronic wounds in patients with compromised wound healing remain a persistent clinical challenge. One example of a chronic wound, diabetic foot ulcers (DFUs), are prevalent in 16.5million diabetics and 25% of diabetics will get a DFU in their lifetime; these wounds are infection-prone and have the devastating consequence of lower leg amputation. Tissue engineering approaches have been effective to some extent clinically in wound healing; however, in chronic challenging wound cases (e.g., DFUs), the optimum biomaterial scaffold still eludes us.


A key focus in the Kearney Lab (http://www.rcsi.ie/index.jsp?p=250&n=544&a=4804) is the development of drug delivery systems that can be triggered to release signaling factors at precise timepoints and the integration of these systems into tissue engineering scaffolds. These platforms are then used to interrogate the effect of bioactive factor timing on tissue regeneration. By understanding the effect of cue timing, enhanced signaling profiles can be achieved; by incorporating this technology inside a tissue engineering scaffold, more effective tissue engineering devices can be developed.


A postdoctoral position (2 to 3 year post) is currently available in the newly renovated and expanded state-of-the-art Tissue Engineering Research Group (http://www.rcsi.ie/tissueengineering) laboratories in the main RCSI building beside St Stephen's Green.  The project will focus on the development of a biomaterial scaffold platform with the capability for on-demand delivery. The platform will then be tailored for application in diabetic foot ulcers. Aside from the core research project, transferable skills and career development will be strongly supported by Dr. Kearney, TERG and RCSI. In addition, funding is already in place for attendance at both national and international conferences and opportunities to undergo specialised training in collaborator's laboratories in Ireland, the USA or elsewhere will be actively explored.


The Kearney Lab's ethos is to provide strong engineering, scientific and biomedical training within a nurturing and collegial environment to ensure trainees are fully prepared for (what we expect to be!) exciting careers.



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