Principal Scientist in Computational Protein Design and Data Modelling

Måløv, Greater Copenhagen area
Salary will match qualifications
September 08 2017
Position Type
Full Time
Organization Type

Are you interested in providing scientific leadership within Computational Protein Design and Data Modelling? And do you like an international and challenging research environment, where you will actively work on identifying the next generation medicines and new therapeutic options that will change the life of patients with diabetes and other serious chronic diseases? Then you may be our next highly valued Principal Scientist.

About the department
At Novo Nordisk you will work in the Modelling department a part of Protein Engineering, where you will collaborate closely with a number of other departments within Global Research. In the Modelling department, we are 6 highly engaged PhD scientists that apply both physics based and data driven modelling to projects in the Novo Nordisk research pipeline. We collaborate closely with Global Research scientists to improve Active Pharmaceutical Ingredient (API) and Drug product (DP) designs of our peptides and proteins. We apply explorative data analysis and machine learning to data generated across the organisation and we generate predictive models to support prescriptive decision making in the projects. We use a broad range of molecular modelling tools including Maestro, Desmond, Gromacs, Rosetta and MOE and data tools including MatLab, R and software developed in house.

The position
We offer an exciting and challenging job, where you will share and discuss computational models with highly experienced, qualified and motivated scientists in multidisciplinary research teams. The project teams work in a flexible, collaborative and cross-functional setting with very ambitious scientific goals.

Your responsibility will be to provide structure based and data driven modelling and to drive our computational protein engineering efforts within API and DP design. Research activities will be focused on developing, implementing and using state-of-the-art structural modelling technologies to improve functional and biophysical properties. You will also engage with stakeholders across the international organisation.

You hold a PhD within a computational structural biology discipline, such as Biophysics or Biochemistry, with more than 5+ years of pharmaceutical industry/biotech experience or academic group leadership. You have established an excellent track record and broad knowledge within applying structure based design methods to drug discovery. In addition, experience within programming, statistical analysis, machine learning and cloud computing is preferred.

As a person you use your curiosity to secure that key structural challenges are identified. Your commitment and scientific insights are used to address the core issues and your communication skills enable you to present the results and thereby getting strong impact on project progress. You can collaborate well with people at all levels. Furthermore, you show a positive attitude towards challenges and thrive in an informal working environment. You take the initiative for driving your projects and you are able to stay on top of things in a dynamic working environment.

Working at Novo Nordisk
Your curiosity, skills, dedication and ambition will help us change lives of patients with diabetes and other chronic diseases for the better. In return, we offer you an opportunity to work in an extraordinarily stimulating scientific environment.

For further information, please contact Søren Berg Padkjær at +45 3075 4520.

28 September 2017.