Multiple Postdoctoral Scientist positions are open in the laboratory of Dr. Ryan M. Drenan in the Department of Pharmacology at Northwestern University Feinberg School of Medicine. Dr. Drenan’s research group conducts leading interdisciplinary studies on the neurobiology, physiology, and pharmacology of cholinergic neurotransmitter systems. Of particular interest are studies on nicotinic acetylcholine receptors and their role in nicotine addiction (reward, withdrawal, etc.), movement/motor disorders, and cognitive processing. The lab employs innovative mouse models and genetic techniques to study native receptor systems, including Cre-mediated CRISPR/Cas9 approaches. Experimental work involves behavioral and cellular approaches. The latter includes brain slice patch clamp electrophysiology, including simultaneous two photon imaging of neurons, optogenetic manipulation of cholinergic circuits, and photostimulation of caged ligands. Other optical approaches involve studying cholinergic receptor expression throughout the brain using novel mouse models expressing fluorescently-labeled receptor proteins coupled with confocal and/or super resolution imaging. Dr. Drenan’s group occupies newly-renovated laboratory space in the Searle Medical Research Building at the downtown Chicago campus of Northwestern University.
The Department, under the leadership of Magerstadt Professor and Chair, Dr. Alfred L. George, Jr., has particular strengths in the areas of neuropharmacology, neurobiology, physiology, and biophysics of ion channels and receptors. Feinberg School of Medicine is an outstanding neuroscience environment, and there are many opportunities for collaboration with labs in other departments such as Physiology, Psychiatry and Behavioral Sciences, Neurology, Opthamology, and Cell and Molecular Biology. Northwestern University and the city of Chicago offer unparalleled cultural and professional opportunities for postdoctoral scholars and their families.
The successful applicant should be a molecular or cellular neuroscientist with a Ph.D. in pharmacology, neuroscience, cell biology or related fields. Prior experience with patch clamp electrophysiology and/or two photon imaging is highly preferred. Individuals with experience in behavioral techniques are also encouraged to apply. Interested individuals should send a detailed CV with bibliography, a brief statement of research accomplishments and future interests (max one page), and three strong letters of recommendation to email@example.com.