La Jolla, CA
August 08 2017
Life Sciences, Biology
Position Type
Full Time
Organization Type
Job Type


Sanford Burnham Prebys Medical Discovery Institute (SBP) is an independent nonprofit medical research organization that conducts world-class, collaborative, biological research and translates its discoveries for the benefit of patients. SBP focuses its research on cancer, immunity, neurodegeneration, metabolic disorders and rare children’s diseases. The Institute invests in talent, technology and partnerships to accelerate the translation of laboratory discoveries that will have the greatest impact on patients. Recognized for its world-class NCI-designated Cancer Center and the Conrad Prebys Center for Chemical Genomics, SBP employs about 1,100 scientists and staff in San Diego (La Jolla), Calif., and Orlando (Lake Nona), Fla. For more information, visit us at or on Facebook at and on Twitter @SBPdiscovery.

Research Description

Applications are invited from ambitious, independent and motivated candidates to work with Professor Peter D. Adams to investigate the epigenetics of aging and cancer at Sanford-Burnham-Prebys Medical Discovery Institute, San Diego. Specific projects in the lab range from development of novel epigenetic therapies to combat cancer (for example, epigenetic therapies to synergize with immune therapies), to investigation of epigenetic mechanisms that contribute to age-associated increase in cancer. A long-term goal of the lab is to develop epigenetic-based approaches for cancer chemoprevention.

The project will employ state-of-the-art molecular and cellular biology approaches, including ChIP-seq, RNA-seq, ATAC-seq, DNA methyl-seq and other large-scale epigenomic and chromatin analyses, including at the single-cell level; high throughput chemical and RNAi/CRISPR phenotypic screens; cell imaging; state-of-the-art gene manipulations using RNAi and CRISPR technology. In addition, we routinely employ sophisticated mouse models and human tissues.

The lab strives to be highly collaborative with other labs in San Diego, the US and elsewhere, for example collaborating with computational biologists, immunologists, experts in specific mouse models of cancer and aging, and surgeons, pathologists and clinical oncologists. San Diego is an outstanding scientific environment and a fabulous place to live.


Candidates should have, or be working towards, a PhD or equivalent degree in a biological science. Expertise in an aspect of cell and/or molecular biology and/or animal models is essential. The lab has dedicated computational biology support for data analysis, so computational expertise is an advantage, but not essential. Successful applicants will be able to learn computational approaches for analysis of large datasets, a big advantage in a competitive job market.

Interested candidates should submit one PDF with a summary of achievements and research interests, updated CV and contact information for 3 letters of references.

Current Lab website:

To apply for the position (Postdoctoral Associate – Adams Lab), please access the Careers page of our public website at:

Sanford Burnham Prebys Medical Discovery Institute is an Equal Opportunity Employer – M/F/Veteran/Disability – committed to the hiring, advancement and fair treatment of all individuals.

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