ADME Principal Scientist Job

Boston, MA, US
July 31 2017
Organization Type
ADME Principal Scientist:PHA001384


Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its legacy for over a century. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases.

Merck is a global health care leader with a diversified portfolio of prescription medicines, vaccines and consumer health products, as well as animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us.

Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of people like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.

This position will contribute to Merck's drug discovery and clinical development efforts in the Department of Pharmacokinetics, Pharmacodynamics and Drug Metabolism (PPDM) at MRL Boston. The primary role of the successful candidate will be to contribute to drug discovery and/or development teams across therapeutic areas, from target validation to patients. The successful candidate will be a scientific leader, with a passion for designing and interpreting studies utilizing in silico, in vitro and in vivo approaches to improve our success in inventing differentiated medicines. A record of accomplishment of successful collaboration while working in cross-functional project teams is expected. The successful candidate will also have responsibility for mentoring and training scientists, as well as contributing to setting global ADME strategy. Responsibilities will also include presenting to senior leadership as well as preparing documentation for regulatory submissions.



- Bachelor’s degree with 14+ years relevant experience, Master’s degree with 10+ years experience or PhD with 8+ years experience. Relevant subjects for highest degree include biochemistry, chemistry, pharmacology or chemical engineering.


- 8+ years of experience serving on multidisciplinary drug discovery and/or development project teams
- Strong scientific background in pharmacokinetics, pharmacodynamics and drug metabolism sciences
- Experience in writing documentation for regulatory submissions
- Established external scientific reputation (e.g. publication record, leadership in consortia, external presentations)
- Excellent communication, mentoring, influencing and leadership skills


- Experience in peptide and/or biologics drug discovery
- Experience of in-licensing Due Diligence activities

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life.

If you need an accommodation for the application process please email us at

Search Firm Representatives Please Read Carefully:

Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck. No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.

Visa sponsorship is not available for this position.

For more information about personal rights under Equal Employment Opportunity, visit:

EEOC Poster

EEOC GINA Supplement​

Merck is an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations.

Primary Location: NA-US-MA-Boston

Job Type: Full Time

Employee Status: Regular

Travel: Yes, 5 % of the Time

Number of Openings: 1

Alternative Work Arrangements Available: Not Available

Relocation Provided: Domestic (within country)

Company Trade Name:Merck

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