Senior Scientist, Chemistry-Chemical Biology Job

South San Francisco, CA, US
July 28 2017
Organization Type
Senior Scientist, Chemistry-Chemical Biology-RES001921


Merck Research Laboratories South San Francisco, a wholly owned subsidiary of Merck and Co., is focused on driving discovery research. Our new multi-disciplinary discovery research site offers state-of- the-art resources to explore the most promising science combined with Merck’s world-class R&D expertise in small molecules and biologics. Located within the heart of the Bay area’s biomedical community, research conducted in our new laboratories spans exploratory biology through early clinical development and is an integral part of Merck’s powerful world-class network of drug and vaccine discovery.

At Merck, we are inspired by the belief that a research-driven enterprise dedicated to scientific excellence can create medicines and vaccines that save and improve lives. Every employee is building on our proud legacy of scientific breakthrough. Our ability to impact the lives of patients worldwide depends on the integrity, creativity, humility and scientific acumen of our team. We are creating a diverse organization that is inspired by invention and founded on a culture of respect and collaboration. At Merck Research Labs South San Francisco, you’ll have the opportunity to expand your knowledge and skills through collaboration with talented and dedicated colleagues while advancing your career.

Merck is currently seeking an exceptional chemist for a Chemical Biology position within the Discovery Chemistry Department located at our South San Francisco, CA site. The successful candidate will join multidisciplinary, highly collaborative discovery teams to invent novel medicines by applying innovative synthetic chemistry, analytical techniques and data analysis to design and synthesize drug candidates and intermediates.

Specific responsibilities will include the following:

- Act as a leader in the laboratory, executing on program and chemistry strategy

- Provide scientific mentoring and technical training of team members

- Design, develop and apply innovative methods and strategies through diverse screening, genomic and proteomic approaches to qualify novel targets and chemoproteomic relationships

- Develop and utilize innovative synthetic and medicinal chemistry problem solving skills coupled with analysis of diverse data sets to build structure-activity relationships

- Design, synthesize, and characterize chemical probes and/or drug candidates in target identification and validation, as well as hit-to-lead through lead optimization projects

- Engage and collaborate with the external scientific community to help identify and validate new targets

- Establish a substantial external scientific presence including authoring significant scientific publications and presentations

To accomplish the above, the successful candidate must have excellent interpersonal, collaboration and communication skills in addition to rigorous scientific thinking and a proven track record of driving the advancement of drug discovery programs.


Education and Experience Requirements:

- Ph.D. in Chemistry with no more than 4 years of industry experience in drug discovery

- Experience in Chemical Biology, as well as, methodology/catalysis, total synthesis, and/or physical organic chemistry, along with a proven track record of solving complex problems.

The quality of our team is essential to our success. We are creating a new and innovative approach to rewarding our employees and establishing a comprehensive value proposition. Our competitive compensation program and benefits are designed to support the wide range of goals, needs and lifestyles of our employees, and the people that matter the most in their lives. If you need an accommodation for the application process please email us at

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for us all.

Merck is an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations.

Job: Research Science

Job Title:Senior Scientist, Chemistry

Primary Location: NA-US-CA-South San Francisco

Employee Status: Regular

Number of Openings: 1

Company Trade Name:Merck

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