Postdoctoral Fellow in Statistical and Computational Genomics

Cambridge, Cambridgeshire
Salary range: £31115 to £39004pa plus excellent benefits
July 27 2017
Position Type
Full Time
Organization Type

Salary range: £31115 to £39004pa plus excellent benefits

Fixed-term for 3 years

A postdoctoral position is available in the Wellcome Trust Sanger Institute under the leadership of Dr Daniel Gaffney. The main research focus of our group is to understand how genetic variants influence cellular functions, using a mixture of statistical genetics, machine learning and high throughput functional genomics data. The successful applicant will have the freedom to develop their own research area within the broad interests of the group. The post-holder will also have access to unique, large-scale functional genomicsdata sets generated in human induced pluripotent stem cells that our group has developed as part of the Human Induced Pluripotent Stem Cells Initiative (

Candidates in Biology with a background in quantitative analysis and population genetics are strongly encouraged to apply. We also welcome candidates with a background in Physics, Statistics or Computer Science with strong interests in computational biology. Excellent programming skills, experience with very large data sets and an ability to work as part of a team are essential. The post-holder will be encouraged to apply for fellowships and work as part of the Gaffney group at WTSI, for more information on the group’s research see:

Dan Gaffney Research Group

Essential Skills

  • PhD in a relevant subject area (Computational Biology, Population Genetics/Genomics, Computer Science, Physics)
  • Strong publishing record
  • Strong statistical and quantitative skills and familiarity with statistical modeling and software
  • Excellent programming skills and extensive experience of UNIX/Linux and cluster computing
  • Ability to communicate ideas and results effectively
  • Ability to work well with other team members
  • Ability to work to tight deadlines

Ideal Skills

  • Previous experience in population genetic analysis
  • Experience with analysis of -omics data sets
  • Some familiarity with the stem cell biology

Other information

The goal of our lab is to understand how regulatory variants alter cellular phenotypes using a variety of experimental and computational approaches. The Sanger Centre offers a world-class academic environment, access to cutting edge sequencing facilities and extensive expertise in genome analysis and human genetics.

The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.

To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops.

Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.

Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.

We seek to provide a supportive family friendly environment to enable scientists at all levels to balance their professional and home lives. This includes options for flexible and part-time working, support and advice for staff taking maternity, paternity, adoption and parental leave an on-site nursery, Campus summer holiday club and childcare voucher scheme.  

Postdoctoral Fellows are typically in their first or second postdoctoral position as part of a period of early career research training. Successful applicant(s) who have submitted their PhD thesis and are awaiting their PhD award are encouraged to apply.

This position is initially for a fixed term of 3 years. For further information please contact Daniel Gaffney on

Closing date: 17th September 2017