Site and clinical features of cancer disease as determinant of thromboembolic recurrences and ble...

Università degli Studi di Perugia
July 24 2017
Position Type
Full Time
Organization Type

In patients with cancer the incidence of venous thromboembolism (VTE) is progressively increasing, probably due to the improvement in patient survival and accuracy of VTE diagnosis. In patients with cancer associated VTE, the risk for recurrence is particularly high as well as the risk for bleeding complications associated with anticoagulant treatment. In recent years, new oral anticoagulants were shown to be as effective as and probably safer than vitamin K antagonists for the treatment of VTE. Unfortunately, these clinical trials included only a limited number of patients with cancer. The aim of the proposed research is to asses the difference concerning the epidemiology, clinical presentation and outcome in patients with different types of cancer (lung, colorectal, prostate and breast) during the course of anticoagulant treatment for venous thromboembolism in a study comparing a new oral anticoagulant with the vitamin K antagonists (The Caravaggio Study).

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