Postdoctoral scientist - Cancer Center Amsterdam CRISPR
You will initiate emerging, cutting-edge genome modification technologies across the AMC/VUmc alliance, and advance our expertise in functional cancer genomics for target discovery. We aim to initiate a Cancer Center Amsterdam (CCA) CRISPR-Cas9 research facility that serves basic and translational cancer research labs throughout the entire CCA. The offered assignment embodies the start-up and implementation of this novel CCA facility.
Your tasks as CCA CRISPR facility officer include 1) the dissemination of state-of-the-art CRISPR-Cas9 knowledge and technology across the CCA, and 2) hands-on laboratory implementation of novel CRISP-Cas9 developments in relation to specific research projects, in collaboration with a team of CCA researchers at AMC and VUmc sites
Specific research projects involve the optimization of precise gene editing in different cancer cell model systems, designing tools for controlled gene activation and inhibition, implementing dead-Cas9 based intracellular labeling and tracing methods, and CRISPR-Cas9 library development for functional genomic screens. The proposed projects are aimed at deepening our understanding of fundamental cancer biological processes, e.g. in relation to cancer immunology, oncogene function, biomarkers, or the identification of targetable genes in different cancer model systems.
This job comes from a partnership with Science Magazine and