Post-Doctoral Researcher in Proteomics (m/f)
The Luxembourg Institute of Health is a public research organisation at the forefront of biomedical sciences. With its strong expertise in population health, oncology, infection and immunity as well as storage and handling of biological samples, its research activities impact on people's health. At the Luxembourg Institute of Health, devoted scientists investigate disease mechanisms to develop new diagnostics, innovative therapies and effective tools to implement personalised medicine. The institution is the first supplier of public health information in Luxembourg, a dynamic multicultural country in the heart of Europe with a strong Research and Development culture supported by important financial and organiational resources. It offers state-of-the-art facilities and an excellent training environment for early-stage researchers, in particular in Life Sciences. The landscape of languages in luxembourg is very diverse. Besides the three official languages of luxembourg: luxembourgish, german and french everyone speaks english, creating a real multilingual environment.
Deregulated signaling of receptor tyrosine kinases (RTK) are a hallmark of glioblastomas (GBM) and many therapeutic attempts are undertaken to interfere with hyperactive intracellular signaling. Attempts to map the exact phosphorylation status of the RTK substrates is hampered by complicated phosphorylation pattern. By combining the extensive expertise in both Mass Spectrometry and GBM Biology at the Luxembourg Institute of Health, this project aims to characterize and quantify phospho-sites involved in GBM cell signaling with superior level of accuracy.
The proteomics laboratory is equipped with the latest instrumentation in high-resolution mass spectrometry. Close collaborations with the other groups of the LIH offer a wide spectrum of modern techniques. Especially the close collaborations of the proteomics laboratory with the bioinformatics group allows the rapid development of specialized techniques and tools to address specific scientific challenges.
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