Genome Engineering Specialist

MRC, The Mary Lyon Centre
Harwell Campus
£27,629, - £32,975 per annum
July 19 2017
MLC 588
Organization Type

Genome Engineering Specialist

MRC, The Mary Lyon Centre

Harwell, Oxfordshire

Fixed Term, until 31st Jan 2020

£27,629, - £32,975 per annum

About Us

The MRC Harwell Institute is recognised as an international centre of excellence in mouse genetics. Within this context, the mouse is used as a model organism for investigating the causes of genetic disease in man. The Institute comprises two closely integrated partners, the Mammalian Genetics Unit and the Mary Lyon Centre.

About the Role

We require a skilled molecular biologist to support a busy genome engineering service for 3 years, in the first instance. You will work in the Molecular and Cellular Biology group, with close collaborations with the Gene Delivery and the Genotyping and Mutation Screens (GEMS) core facilities.

The MLC undertakes generation and quality control of mouse targeted alleles, for both large-scale mutagenesis programmes or as a bespoke service for individual laboratories. You will be based in the Molecular and Cellular Biology group and coordinate the genome engineering work at the MLC. You will work in a twelve-strong team under the guidance of the Molecular and Cellular Biology Deputy Manager. You will be responsible for the design, implementation and quality control of new alleles, with the support of two research assistants. In addition you will communicate with MLC’s customers, other relevant MLC departments and present the work of the service in conferences and courses.

About You

Strong molecular biology and organisational skills are essential. Experience in the handling of either CRISPR reagents and RNAs or generation of complex plasmid based-constructs is desirable but not essential, as training can be provided.


We are strongly committed to your personal development and well-being, with extensive opportunities for training and flexible working.  Choosing to come to work at the MRC means that you will have access to a whole host of benefits, from a final salary pension scheme and 30 days of holiday entitlement plus bank holidays, to access to employee shopping/travel discounts and salary sacrifice cycle to work scheme and childcare vouchers.

For full details of this post and to complete an online application, visit and upload your CV along with a covering letter stating why you are applying for this role.  Please quote reference number MLC 588.

Closing date: 30 July 2017

The MRC is an equal opportunities employer.

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