Postdoctoral/PhD Position: Single-Cell Analysis of Differentiation

Radboud University
July 11 2017
Position Type
Full Time
Organization Type

One of the key challenges of regenerative medicine is to obtain mature differentiated cells for use in patients. This ambitious project will focus on human stem cells and differentiated stem cells to study chromatin state and the gene regulatory interactions underlying cellular identity.

As a postdoctoral researcher/PhD candidate you will use single-cell transcriptome analysis (single- cell RNA-seq) to distinguish subpopulations of cells with different identities and potential, and you will compare these transcriptomes to those of mature human cells. You will also obtain chromatin accessibility and epigenetic data (ATAC-seq, ChIP-seq) to examine gene-regulatory elements and to infer gene regulatory networks. You will use these data to predict and test key regulatory interactions with the aim of improving the maturation of differentiated stem cells. You will have the opportunity to develop novel ideas and work on an independent project that aligns with our research interests.

This job comes from a partnership with Science Magazine and Euraxess