Postdoctoral and scientist

Location
Philadelphia, Pennsylvania (US)
Salary
NIH guideline-based salary plus benefits
Posted
June 08 2017
Position Type
Full Time
Organization Type
Academia

Postdoctoral and scientist positions are available to study exciting research projects supported by NIH and other foundations in the Shriners Hospitals Pediatric Research Center (SHPRC) at Temple University in Philadelphia. The major goals of these projects are to study axon regeneration, neural repair and myelination in the CNS and to develop effective strategies for neural repair. The projects are aimed to: 1) investigate the molecular and cellular mechanisms underlying neuronal damage, growth failure and demyelination in the CNS, and 2) develop novel and effective approaches to promote neuronal regeneration, neural repair, remyelination, neuroplasticity and functional recovery after injuries or in neurodegenerative disorders.  We employ various in vitro and in vivo research approaches, including molecular and cellular neurobiology, genetic and pharmacological methods, viral gene delivery, biochemistry, and multiple neuronal/axonal lesion models (such as spinal cord injury, optic nerve crush and experimental autoimmune encephalomyelitis) in rodents. We are highly interested in identifying novel genes that regulate neural functions and regeneration with various molecular, transgenic and viral vector approaches. You are encouraged to find further information on the research program from our publications [see: Brain Behav Immun. 2017, PMID: 2855901; J Clin Invest. 2016 Jun 1;126(6):2321-33; Sci Rep. 2016 Nov 16;6:37152; Nature. 2015 Feb 19;518(7539):404-8; Biomaterials. 2014 May;35(16):4610-26; J Neurosci.  2011 Oct 5;31(40):14051-66;  J Neurosci.  2010 Jan 20;30(3):963-72;  J Neurosci. 2008 Sep 3;28(36):8914-28;  J Neurosci. 2007 Apr 11;27(15):4154-64; J Neurosci. 2004 Nov 17;24(46):10511-20;  J Neurosci. 2003 May 15;23(10):4219-27, Neuron. 2003 Apr 24;38(2):187-99, and Nature. 2002 May 30;417(6888):547-51].  You may also visit our Center website for additional information (https://medicine.temple.edu/departments-centers/research-centers/shriners-hospitals-pediatric-research-center/about).

Highly motivated individuals with a strong background in animal models (neuronal, axonal or myelin injury), viral vector, histology, behavioral tests, molecular and cellular neurobiology, biochemistry and genetic approaches are encouraged to apply. The candidates with research experience in neural repair, neuronal regeneration, myelination, viral vector generation, CNS injury, or neurological disorder models will be considered favorably. Candidates should have a PhD, MD/PhD or equivalent in the field of neuroscience, molecular/cellular biology, biomedicine or biochemistry. Following appropriate training, the successful applicants will have ample opportunity to develop new research skills and to perform innovative and cutting-edge research funded projects. Successful applicants will be paid with NIH guideline-based salary plus benefits and will become the members of a high-motivated research team in collaborations with other excellent research labs. The research in SHPRC is focused on neural repair and regeneration and this Center provides outstanding research facilities and environment for various levels of trainees and scientists. Temple University is exceedingly diverse in all aspects of University life and is an Equal Opportunity/Affirmative Action Employer. Please send curriculum vitae or enquiry to Dr. Shuxin Li (Shuxin.li@temple.edu).

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