A position is available in the laboratory of Jae-Won Shin, Ph.D., for a highly motivated postdoctoral fellow to work in an interdisciplinary research environment at the interface between biomedical science and engineering.
The postdoctoral fellow will work on integrative approaches to investigate how biophysical forces impact mesenchymal stem cell functions to modulate blood, lung and vascular systems. To both manipulate and measure physical forces exerted on cells, we use various microtechnologies, including micropipetting, atomic force microscopy, and microfluidics. These methods are used in combination with molecular biology and protein biochemistry to reveal mechanobiological insights behind force-dependent regulation of cell-cell communications. Fundamental insights from these efforts are aimed at developing multiscale biomaterial strategies for tissue regeneration by designing stem cell and organoid products ex vivo, controlling cell delivery in vivo, and targeting cells in situ.
The Principal Investigator will help the applicant develop his/her career by providing a dynamic and collaborative research environment. The PI will encourage the preparation of research papers, application of fellowships, and presentation at national/international meetings.
The laboratory website: http://sculptingregeneration.org
The Department of Pharmacology at the College of Medicine (http://mcph.uic.edu) has a dynamic group of junior and senior faculty, research faculty, postdoctoral fellows and PhD students. The department's strengths are in the broad areas of cell signaling, cardiovascular and lung biology, stem cells and regenerative medicine, and drug discovery. The Department leads the field in funding and is home to a world-class graduate pharmacology program. In 2016, we were ranked 7th in the nation in our field in NIH research funding and in 2017, we were ranked in the top 11 in the United States based on QS World University Rankings by Subject in Pharmacy and Pharmacology.
The postdoctoral fellow is expected to develop and learn to utilize various techniques in both biological (e.g. molecular biology and protein biochemistry) and physical sciences (e.g. atomic force microscopy, micropipetting, biomaterial design, and microfabrication). To facilitate this effort, the fellow will have an access to various state-of-the-art facilities in the University of Illinois at Chicago campus (http://www.rrc.uic.edu), and other major institutions in the Chicago area through the Chicago Biomedical Consortium (http://www.chicagobiomedicalconsortium.org).
1) Candidates must have a Ph.D. or M.D./Ph.D. degree.
2) Expertise in at least two of the following areas:
- Polymer chemistry to design biomaterials, including nanoparticles and hydrogels
- Fabrication and measurement at micro and nanoscales: e.g. microfluidics, microfabrication, micropipetting, and atomic force microscopy
- In vitro cell biology and engineering: e.g. primary cell isolation, FACS, 3D cell culture, confocal microscopy, and cell surface engineering
- In vivo animal studies (rodents): e.g. breeding, transplantation, survival surgery, and in vivo imaging
3) Minimum of two first-author primary research articles in international journals.
4) Excellent verbal and written communication skills in English.
Interested applicants who meet all the criteria above should send a PDF file which includes a cover letter stating career goals, CV, and contact information (including email addresses and phone numbers) for three references to Jae-Won Shin, Ph.D. Email to: email@example.com