PhD Position: Host Pathogen Interactions Driving Viral Pathogenesis (1.0 FTE)
To elucidate host interactions that drive the pathogenesis of viruses we, at the Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, have recently developed a novel technique based on tissue biobanks. Animal tissues collected during necropsies are used to generate multispecies and monospecies tissue arrays, which allow studying the requirements for binding of attachment proteins of pathogens.
We are now looking for a highly motivated PhD candidate (1.0 FTE) to generate novel veterinary tissue biobanks to study viruses that cause not yet understood diseases including zoonoses, in companion animals, as well as farm animals and wild life species. By using recombinantly expressed proteins of for example coronaviruses and orthomyxoviruses, we aim to understand the drivers of host and tissue tropism, but also to develop novel antivirals, vaccines and diagnostic strategies. Our strategy has already revealed novel receptors that are crucial determinants of viral pathogenesis.
The project will be performed in collaboration between the Division Pathology and the Dutch Wildlife Health Centre. The project fits well within the extablished center of excellence on One Health within the Utrecht University and the UMC Utrecht.
We are looking for a highly motivated PhD candidate with a Master degree in Life Sciences, Animal Sciences, or equivalent. Experience with protein-based techniques is preferred, as well as broad interest in animal diseases and the pathology of infectious diseases. The multidisciplinary approach of this project requires a candidate that is flexible, has good communication skills and has very good command of the English language, both written and oral.
This job comes from a partnership with Science Magazine and