Sr. Research Associate, Process Development

Employer
Moderna
Location
Massachusetts
Salary
Competitive
Posted
March 15 2017
Discipline
Life Sciences, Biology
Organization Type
Biotech
Sr. Research Associate, Process Development

Position Summary

The primary responsibilities for the Research Associate or Sr. Research Associate, Process Development will be to support the Process Development team to develop and scale-up messenger RNA therapeutics. The scientist/engineer will be involved in clinical study enabling scale-up and pilot production of mRNA. The position will partner closely with Process Sciences and Production teams, and the candidate must be able to work in a multi-disciplinary environment.

Responsibilities

  • Work as a team to execute pilot production of mRNA
  • Develop and evaluate scale-up and scale-down process models
  • Design and conduct experiments to enable process improvements
  • Support process transfers to external collaborators
  • Support cross-functional projects with Process Sciences and Analytical Development teams

Minimum Qualifications

  • 2-4+ years relevant industry experience
  • BS in Chemical Engineering, Chemistry, Biochemical Engineering, Biochemistry or closely related field
  • Hands on experience with purification techniques including UF/DF, ion exchange chromatography, affinity chromatography
  • Experience with process scale-up / scale-down
  • Experience with AKTA purification systems
  • Experience with enzymatic reactions is a plus
  • Knowledge of statistical design of experiments (DoE) and analysis
  • Knowledge of nucleic acid chemistry and biology is a plus
  • Knowledge of GMP and GLP regulations

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