Engineer, Formulation Delivery and Technology

Employer
Moderna
Location
Massachusetts
Salary
Competitive
Posted
March 09 2017
Discipline
Life Sciences, Biology
Organization Type
Biotech
Engineer, Formulation Delivery and Technology

Position Summary

The engineer in this role will build capability within the formulation group for early stage novel pre-candidate selection formulation and process development.  Interfacing directly with Drug Product Sciences to enable development of scaled processes for novel formulations testing, stability assessment, and progression of formulation improvements from discovery toward development.

Responsibilities

  • Facilitate process development and composition exploration for novel nanoparticle formulations
  • Thoroughly characterize impact of process variables on formulation characteristics
  • Support early scale-up and early stability evaluations of novel nanoparticle formulations
  • Provide design support and experimental execution for process evaluation and customization
  • Develop processes for critical attribute control during processing and storage
  • Accountability for project success and results delivery
  • Collaborate and interact closely with formulation group and other project team members
  • Communicate findings to project team and broader organization

Qualifications

  • Chemical engineer or materials scientist with 2-5 years of industry experience in nucleic acid nanoparticle process development
  • Experience with optimization of biopharmaceutical unit operations
  • Experience with scaling of drug product manufacturing processes from bench to early phase clinical scale
  • Use of designed experiments and associated statistical methods for process and design space optimization
  • Knowledge of biophysical and analytical techniques for characterization of nanoparticle systems, as well as working understanding of QbD principles
  • Outstanding communication skills (verbal and written)
  • Ability to multitask multiple projects in a fast-paced environment
  • Intrinsic drive to effectively collaborate in a dynamic, cross-functional matrix environment

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