Senior Scientific Researcher, Protein Chemistry

South San Francisco, California
March 16 2017
Position Type
Full Time

Join a Team that Lives to Improve Lives

People come to Genentech from across disciplines and across the world to solve our most challenging medical conditions. You’ll find inspiration in our passion for biotechnology, our purpose to positively impact the lives of millions of patients and our dedication to our people. Joining Genentech means being part of a tradition of inquiry that will change the world. It means embracing our failures as much as our successes. It requires a willingness to look beyond the edge of what's possible. And a focus on doing the day-to-day work that makes great science happen.

The following opportunity exists in our South San Francisco, CA headquarters:

Senior Scientific Researcher, Protein Chemistry


We have an exciting position for a Bioconjugation Chemist, Protein Chemist, or Protein Engineer at the scientific researcher/senior scientific researcher level to join the Protein Chemistry department. This position will involve research in the area of bioconjugation methods, polymer synthesis for covalent protein arrays, and the preparation of protein-polymer conjugates, as it relates to the development of hybrid protein therapeutics for the treatment of a variety of diseases. Depending on the candidate’s expertise, responsibilities will include developing new bioconjugation strategies, polymer synthesis, protein-polymer conjugation and protein purification. The individual will also be responsible for rigorous analytical characterization of polymers, proteins, and conjugates. The individual will be expected to work independently in the lab but collaborate with colleagues across various functional areas at Genentech. The candidate will provide synthesis and characterization of complex bioconjugates to programs from basic research through early development, and they are expected to generate and communicate results that meaningfully impact project decisions. The successful candidate will also be expected to contribute to high-impact publications related to the job responsibilities and present at scientific conferences.

Who You Are

A MS or PhD in chemical biology, biology, protein chemistry, biochemistry, biophysics or a related discipline. A candidate with an MS requires 6+ years of experience in related work. A PhD needs 2+ years of technical experience in these or related areas. Candidates should have demonstrated expertise in bioconjugation to proteins and/or polymers, with a proven track record of publications that are relevant to production of complex protein arrays. The work will involve the design and application of polymer synthesis and/or protein-polymer bioconjugation It will also involve analytical methods including those used for polymer synthesis (NMR, preparative RP, LC/MS, GC/MS, etc.) and/or bioconjugation (HPLC/UHPLC, LC/MS, FPLC, affinity purification, gel filtration, SEC-MALLS, ion exchange chromatography, etc). Expertise with standard text, graphic, and presentation software is required. Excellent communication and interpersonal skills are essential and will be heavily evaluated during the interview process. The ideal candidate will be motivated, and have strong problem-solving, troubleshooting, communication, and organizational skills.

A Job with Benefits Beyond the Benefits

No matter who you are or what role you play, you’ll help change the face of medicine and make a real difference in the lives of people facing the most challenging medical conditions. Plus, you’ll thrive in our one-of-a-kind culture, where diversity is celebrated, employees are valued for their contributions and we all serve as advocates for change who continually find ways to do things better.

The next step is yours. To apply today, click on the "Apply" button below.

Genentech, a member of the Roche Group, has multiple medicines on the market for cancer and other serious illnesses.

Genentech is an Equal Opportunity Employer: Minorities/Women/Disability/Veteran

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