PhD-candidate at NUTRIM / Department of Genetics & Cell Biology
The incidence of metabolic and cardiovascular disorders is steadily increasing in Western societies. Current observations suggest that inflammation of the liver, also called non-alcoholic steatohepatitis (NASH), is the hepatic manifestation of the metabolic syndrome. NASH sets the stage for further chronic liver injury, including liver cirrhosis. Therefore, it is important to diagnose and treat NASH, however, until now there are no good non-invasive diagnostic tools or treatment options available.
In this PhD project, your aim will be to discover novel underlying molecular mechanisms of NASH. The identified novel targets will be evaluated for their potential to diagnose and treat NASH in cell culture and eventually, in NASH patients.
The following techniques will be used: cell culture, (immuno)histochemistry, Western blotting, RT-PCR, biochemical lipid measurements, ELISA and chemical analytical techniques.
The ideal candidate:
- Holds a Master's degree in life sciences or an equivalent scientific degree
- Has a high level of personal motivation, commitment and enthusiasm to work in a team
- Is willing to extend his/her capabilities, practical skills and scientific knowledge
- Is open to feedback and communicates in a clear manner
- Is well-organized and an independent style of working with regard to time and quality management is an advantage
This job comes from a partnership with Science Magazine and