Research Scientist-Immunology and Autoimmunity

San Diego
February 10 2017
Life Sciences
Position Type
Full Time
Organization Type
Job Type
The Immunology discovery research group at Lilly's Biotechnology Center in San Diego seeks a Ph.D. level scientist with deep knowledge and research experience in immunology and autoimmunity to join a team responsible for developing novel therapeutics for the treatment of autoimmune and inflammatory diseases. Activities include target identification and validation, development of therapeutic compounds with an understanding of the mechanism of action and biomarker strategies. The ideal candidate is a highly motivated team player, with a passion for scientific research and drug discovery, and possessing a broad knowledge of immunology particularly in innate immunity, to drive and support preclinical and clinical development of the broader Lilly immunology portfolio. The successful candidate should also have a track-record of high quality publications in peer-reviewed journals.

Key Objectives/Deliverables:
  • Utilize cutting edge knowledge, technology and assays to design and execute experiments that identify and validate targets for our immunology portfolio.
  • Collaborate with cross-functional partners within Lilly and externally to deliver novel, differentiating drug candidates for clinical development; to understand their mechanism of action, biomarkers and opportunities for patient tailoring.
  • Remain tightly connected to the external academic and biopharma communities to source ideas, collaborations and technologies to drive novel target and molecule discovery.
  • Serve as a source of state-of-the-art scientific knowledge in the field of innate immunity especially in the areas of dendritic cell, innate lymphoid cells and macrophage; exert influence on research direction and selection of drug targets.
  • Record, analyze and communicate scientific ideas and data to governance committees and managers and project teams with clear interpretation of hypothesis and results
Basic Qualifications
  • Ph.D. in Immunology or related discipline or field of study
  • At least 2 years of postdoctoral research experience preferred.
Additional Skills/Preferences
  • Expertise in cellular/molecular immunology of human and animal immune systems, particularly in innate immunity biology with deep knowledge of dendritic cell, innate lymphoid cell and/or macrophage biology.
  • Knowledge of pharmacology with experience in various autoimmune and inflammatory animal disease models
  • Excellent interpersonal skills and collaboration/team spirit.
  • Track record of scientific success demonstrated by authorship on high quality publications in top tier peer-reviewed journals, and/or patents.
  • Recognized as a scientific expert in immunology, inflammation and autoimmune disease, with a focus on the pathogenic functions of innate immunity.
  • Has deep expertise in working in vitro with primary human/rodent tissues and cells, and experience with various autoimmune/inflammatory animal disease models.
  • Knowledge and experience in investigating immune cellular interaction, synapse formation and function as well as receptor signaling/function for cell-cell interactions and immune responses.
  • Has a truly innovative mind that lends to the development of solutions to complicated and complex biological problems.
  • Ability to critically evaluate scientific literature, identify and validate potential targets and develop strategic approaches to research and projects.
Additional Information
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Lilly credits its exceptional employees for its successes, and knows the key to ongoing achievement lies in attracting and retaining the best people. A company rich in heritage, Lilly employs individuals, conducts research and markets products worldwide. By providing for the unmet needs of our customers through a continuous stream of innovation, we will outgrow all competitors.

Lilly earns consistent and wide recognition for creating an exceptional work environment:
•Business Week magazine 50 Best Places To Launch A Career™
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•Industry Week magazine 100 Best-Managed Companies™
•Science magazine Best Companies for Scientists™