Liver Discovery Research Lead

Philadelphia, Pennsylvania (US)
Base salary, bonus, benefits, and RSU's
April 21 2017
Position Type
Full Time
Organization Type

The Liver Discovery Research Lead will manage the Liver functional group within the Discovery Research group under Translational Research. He/she will be responsible for:

·         Providing leadership within in a group of scientists/research associates, to develop pre-clinical programs from early discovery to the clinic.

·         Initiate and oversee joint programs with academic collaborators.

·         Establishing project timelines and ensuring work is completed according to schedule.

·         Training and developing staff at varying levels of experience.

The Liver Discovery Research Lead position requires extensive translational experience with gene therapies targeting the liver, including: 

·         In-depth familiarity with target validation and lead identification/optimization, using a combination of molecular, cellular and in vitro/in vivo techniques for hepatic gene therapy programs.

·         Familiar with delivery techniques targeting the liver and have substantial experience with studies in laboratory animals.

Some familiarity with AAV, as well as some knowledge of clinical trial design and regulatory strategy, is preferred.

Required Skills:

·         Ph.D. in relevant scientific discipline (e.g. cell and molecular biology, biochemistry, etc.)

·         Minimum 5-8 years of hands-on experience in the field of gene therapy.

·       Previous management or supervisory experience strongly preferred.

·         Extensive hands-on experience in hepatic gene therapy techniques, such as intravenous injection, hepatocyte isolation, etc.

·         Strong organizational skills.

·         Excellent writing and verbal communication skills.

·         Previous management experience preferred, but not required.

·         Strong publication record is a plus.

 ·         Experience with AAV vectors is a plus.

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