Postdoc Positions for Molecular Cancer Biology and Bioinformatics

Location
Pittsburgh, Pennsylvania
Salary
minimum salary: $47,476
Posted
January 12 2017
Position Type
Full Time

Two Postdoctoral positions are available at Wang laboratory of University of Pittsburgh Cancer Institute, Departments of Pathology and Biomedical Informatics. The individuals will be working on integrative genomics initiatives aimed at identifying pathological genetic aberrations, predictive biomarkers, and therapeutic targets in aggressive breast cancers from next-generation sequencing and genomic datasets. The candidates will receive unique multidisciplinary training on cancer biology, translational studies, and integrative analysis of multi-dimensional genomic datasets. Candidates must have a Ph.D. degree. Preference will be given to those with an outstanding publication record in cancer research, and those with established experimental skills in cancer cell biology or integrative bioinformatics.

The research topics for Molecular Cancer Biology include studying recurrent gene fusions, predictive biomarkers, therapeutic targets, and targeted agents in clinically intractable breast cancers. The primary responsibilities include experimental validation of newly discovered cancer genes and targets, characterize their molecular basis, confirming their role in tumor initiation, progression, and therapeutic resistance in vitro and in vivo, elucidating their action mechanisms, and exploring clinical applications. The research topics for bioinformatics include development of novel analyses to analyze whole-genome sequencing data, integration of multidimensional cancer genomic datasets to identify cancer targets, and development of innovative bioinformatics tools for genomics-guided precision medicine of cancer patients.

Wang laboratory is a multidisciplinary cancer genomics and molecular targeting lab that combines computational and experimental approaches. The long-term goal of this lab is to apply a multiple disciplinary approach inclusive of bioinformatics, genetics, molecular and cell biology, and translational studies to discovery driving genetic aberrations and qualify viable cancer targets on the basis of multidimensional genomic datasets generated by Cancer Genome Projects. The lab is currently funded by two R01 grants. Postdoc trainees in this lab have received multiple prestigious fellowship awards including two awards from Congressionally Directed Medical Research Programs of the Department of Defense, and two awards from Susan G. Komen for the Cure Foundation. For more information about their research, please visit their website: http://www.cagenome.org/lab/.

To apply, please send your CV, cover letter, and the contact information of 3 referees to:

Xiaosong Wang, M.D. Ph.D.,

Associate Professor of Pathology and Biomedical Informatics

University of Pittsburgh Cancer Institute

Email: wangx13@upmc.edu

The University of Pittsburgh offers a comprehensive salary program and excellent benefits in a smoke and drug free workplace. University of Pittsburgh School of Medicine is an Affirmative Action/Equal Opportunity Employer and encourages applications from under-represented groups.

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