Computational Biologist (Staff Scientist)

Cambridge, Cambridgeshire
Salary range £31498 to £39729 pa plus excellent benefits.
December 13 2016

The Human Cell Atlas team at the Wellcome Trust Sanger Institute is looking for an exceptional Computational Biologist (Staff Scientist) to work on projects supporting and delivering this exciting large-scale international initiative. Work in this post will encompass projects involving research and development, optimisation and implementation of cutting-edge techniques and methods that will eventually underlie work towards the Human Cell Atlas. This will require mostly work in single-cell genomics and transcriptomics along with the potential for methods to analyse gene expression in a spatial context. There will also be opportunities to work on the development of novel and innovative algorithms for single-cell data analysis. 

In addition, the successful candidate will be involved in pilot projects to generate data for the first draft of the Human Cell Atlas by analysing single-cell RNA-sequencing from human tissue samples. This post will involve extensive interactions with research groups throughout the Sanger Institute and the Wellcome Genome Campus.

Essential Skills

  • PhD (or equivalent) in a computational or biological science
  • Ability to independently solve complex scientific/technical problems and manage scientific projects
  • Strong experience or formal training in computational biology or bioinformatics and familiarity with genomics
  • Demonstrated proficiency with several of the following technologies: R, Unix, Perl, Python, Java, Matlab, C, C++
  • Experience working with Next Generation Sequencing data, particularly RNA-seq data
  • Excellent communication skills
  • Self-motivation and diligence
  • Ability to work as part of a team

Ideal Skills

  • Postdoc experience
  • Experience with single-cell datasets
  • Understanding of regulatory issues involved in work with human data
  • Good publication track record
  • Experience working in high performance computing environments

Other information

We are looking for a flexible and talented computational scientist with extensive experience and proven success in working with next generation sequencing data. Experience with single-cell genomics would be beneficial. For informal enquiries, please contact Dr. Mike Stubbington (

The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.

The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited’s 100,000 Genomes Sequencing Centre. The Campus is also home to Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus. Its mission is to enable everyone to explore genomic science and its impact on research, health and society.

To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops.

Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.

Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.

Please include a covering letter and CV with your application.  

Closing date for applications:   14th February 2017, however applications will be considered and reviewed on an on-going basis and therefore the post may be filled before the deadline.

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