Early stage researcher PhD position in Controlling Cartilage to Bone Transitions for Improved Tre...

Employer
IRCCS Ospedale San Martino
Location
Italy
Posted
October 31 2016
Discipline
Other
Position Type
Full Time
CarBon is an Horizon 2020 Marie Sklodowska-Curie Innovative Training Network (MSCA-ITN) on controlling cartilage to bone transitions for improved treatment of bone defects and osteoarthritis. 14 Early Stage Researchers (ESRs) will be appointed by the CarBon consortium for 36 months each.



The consortium consists of partners from both academia and industry with excellent scientific qualifications in multiple disciplines. In total, there are 14 open ESR positions within CarBon. Each ESR will be appointed at one of the consortium partners. During the appointment, secondments will be performed at the premises of other partners to ensure multidisciplinary training and close collaboration. The ESRs will start their projects between January and September 2017.



The ESR (ESR2) will focus on the functional characterization of the proteins and extracellular vesicles (EVs) that compose the secretome of human adipose tissue-derived mesenchymal stem cells activated by different stimuli (hypoxic and inflammatory stimuli) in order to identify key factors/EVs involved in the modulation of the endochondral ossification processes. In particular, the deep characterization of EVs will comprehend a proteomic and microRNA profiling. ESR2 will be expected to be involved in the validation of the effects of the selected secretomes on angiogenesis, mineralization and endogenous progenitor cell migration both in vitro and in vivo.



An ideal ESR PhD candidate will hold a Master's degree and have excellent marks from his/her previous studies and courses along with experience in one or more of the relevant fields. Excellent written and oral communication skills are a must. A preferential title will be a previous experience in the stem cell biology field.

This job comes from a partnership with Science Magazine and Euraxess

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