Project Scientist -Muscle Metabolism - Department of Nutritional Sciences & Toxicology
UNIVERSITY OF CALIFORNIA, BERKELEY
PROJECT SCIENTIST POSITION – MUSCLE METABOLISM
DEPARTMENT OF NUTRITIONAL SCIENCES & TOXICOLOGY
The Hellerstein Laboratory has developed techniques to measure the incorporation of 2H2O in plasma, muscle and adipose tissue proteins and lipids, by using sophisticated mass spectrometric approaches. These techniques allow the assessment of metabolic flux rates in various tissues including muscle (proteome dynamics and mitochondrial biogenesis), and plasma (protein fluxes), as well as muscle mass by mass spectrometric label dilution, and metabolic flux rates in various other tissues including the liver (de novo lipogenesis [DNL], TG synthesis, cholesterol synthesis, gluconeogenesis, and fibrogenesis), and adipose tissue (DNL, TG synthesis and turnover rate, adipogenesis, fibrogenesis), The Hellerstein Laboratory at the University of California at Berkeley has considerable expertise in reliably performing and interpreting the data from these complex analyses and invented and validated most of the methods that will be used. Duties and responsibilities will include measurements of muscle protein turnover by mass spectrometry, particularly by use of stable isotope labeling protocols, isotope ratio analyses, and muscle mass-related techniques; management of large data bases, especially those related to proteomics, flux proteomics and muscle dynamics; participation in human and animal stable isotope studies and methodologic design; experimental and biochemical laboratory work in studies related to stable isotope labeling and mass spectrometry, including development of novel methods; ability to work in neurobiology; writing manuscripts, reports, progress notes and grants and interacting with collaborators and scientists who are not mass spectrometrists.
Candidates must have completed a Ph.D. or equivalent degree in chemistry, biochemistry, chemical engineering or related field at the time of application.
Candidates must have a Ph.D. or equivalent degree in biochemistry, physiology, or related field by appointment start date.
Demonstrated experience with muscle metabolism, protein turnover and its measurement by biologic mass spectrometry, particularly with stable isotope labeling protocols, isotope ratio analyses, and muscle mass-related work. The ability to manage large data bases, especially those related to proteomics and flux proteomics related to muscle dynamics. Experience in human and animal stable isotope studies and methods also required. Extensive experimental biology and biochemical laboratory experience in studies related to stable isotope labeling and mass spectrometry, including development of novel methods. Ability to work in neurobiology field also helpful. Experience writing manuscripts, reports, progress notes and grants and experience interacting with collaborators and scientists who are not mass spectrometrists.
The anticipated start date for this position is September 15, 2016. The initial appointment is for one year, with renewal based on performance and funding. This is a full-time appointment.
SALARY AND BENEFITS
The salary range for this position is $79,000 -$118,700. Salary will commensurate with qualifications and experience. Generous benefits are included (http://ucnet.universityofcalifornia.edu/compensation-and-benefits/health-plans/index.html).
Interested individuals should include a 1-2 page cover letter describing their research experience, 1-3 relevant publications, a current CV, and the names and contact information of three references. Letters of reference may be requested for finalists. It is optional to include a statement addressing past and/or potential contributions to diversity through research, teaching, and/or service.
This position will remain open until filled.
Questions regarding this recruitment can be directed to Marc Hellerstein at email@example.com.
All letters will be treated as confidential per University of California policy and California state law. Please refer potential referees, including when letters are provided via a third party (i.e. dossier service or career center) to the UC Berkeley Statement of Confidentiality (http://apo.berkeley.edu/evalltr.html) prior to submitting their letters.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy see: http://policy.ucop.edu/doc/4000376/NondiscrimAffirmAct
The Department is interested in candidates who will contribute to diversity and equal opportunity in higher education through their research or teaching.
The University of California, Berkeley has an excellent benefits package as well as a number of policies and programs in place to support employees as they balance work and family.